{"id":"W2066736865","doi":"10.1111/j.1538-7836.2007.02644.x","title":"A dose escalation study of YM150, an oral direct factor Xa inhibitor, in the prevention of venous thromboembolism in elective primary hip replacement surgery","year":2007,"lang":"en","type":"article","venue":"Journal of Thrombosis and Haemostasis","topic":"Venous Thromboembolism Diagnosis and Management","field":"Medicine","cited_by":107,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hamilton General Hospital","funders":"Astellas Pharma, Netherlands; Astellas Pharma Europe","keywords":"Medicine; Venography; Incidence (geometry); Clinical endpoint; Venous thromboembolism; Surgery; Adverse effect; Cohort; Risk factor; Internal medicine; Anesthesia; Randomized controlled trial; Thrombosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001413547,0.001074794,0.00315834,0.000764213,0.0004020985,0.001002347,0.0009374494,0.001500469,0.002146739],"category_scores_gemma":[0.002582358,0.0006900757,0.001325828,0.0005906482,0.0009177008,0.000829042,0.0003751121,0.003175998,0.0005637949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007729315,"about_ca_system_score_gemma":0.0009861425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001267802,"about_ca_topic_score_gemma":0.001673679,"domain_scores_codex":[0.9990764,0.0004049791,0.00008491721,0.0001493266,0.00008864875,0.0001958216],"domain_scores_gemma":[0.9986093,0.000402253,0.0002174002,0.0001760089,0.00007526934,0.0005197415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8738808,0.05227363,0.004873294,0.000280263,0.001057645,0.0001922738,0.0002816633,0.001132996,0.01474713,0.0001443138,0.0006607437,0.05047525],"study_design_scores_gemma":[0.5388243,0.4403182,0.01654557,0.00002203354,0.0005195771,0.0001873587,0.00006452682,0.001018336,0.001825299,0.00009379523,0.000539604,0.00004148004],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979546,0.0006275101,0.0001859545,0.0001169786,0.00006283045,0.0004610744,0.0001140018,0.00003172776,0.0004454218],"genre_scores_gemma":[0.9971517,0.0005198403,0.0006111429,0.000328622,0.0001476405,0.0004032599,0.0002257103,0.00001135892,0.0006006071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00315834,"threshold_uncertainty_score":0.007475674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07602518966735577,"score_gpt":0.3568914924815502,"score_spread":0.2808663028141944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}