{"id":"W2066779566","doi":"10.1074/jbc.m114.595462","title":"Expression of Non-acetylatable H2A.Z in Myoblast Cells Blocks Myoblast Differentiation through Disruption of MyoD Expression","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University; University of Toronto","funders":"","keywords":"MyoD; C2C12; Biology; Cellular differentiation; Myogenesis; Chromatin; Histone; Ectopic expression; Molecular biology; Cell biology; Myocyte; Genetics; Cell culture; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002820447,0.0001672784,0.000359385,0.00002510709,0.0000204654,0.000008960187,0.0002617766,0.0003495392,0.0000320015],"category_scores_gemma":[0.000110284,0.0001222894,0.0001501856,0.00008105739,0.00008911428,0.00001151764,0.0001715514,0.0001835807,5.181266e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003533022,"about_ca_system_score_gemma":0.00007049629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003465685,"about_ca_topic_score_gemma":8.901567e-7,"domain_scores_codex":[0.9986649,0.00004641038,0.0007129278,0.000199157,0.0001975357,0.0001790506],"domain_scores_gemma":[0.998636,0.00002076798,0.0008202316,0.0002223665,0.000206578,0.00009407358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000315404,0.0002907705,0.005180751,0.00006737247,0.00001357651,0.000002385913,0.00009048077,0.0009468119,0.9927183,8.850503e-7,0.0002609933,0.0001122896],"study_design_scores_gemma":[0.001130272,0.0004468554,0.002581849,0.000180466,0.00001120009,0.0000173521,0.0003507645,0.0002744486,0.994544,0.0001390278,0.0001948286,0.0001289217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961329,0.0003373292,0.003006415,0.0000180256,0.00009604673,0.0000705271,0.0000291318,0.000002115181,0.000307517],"genre_scores_gemma":[0.9968991,0.0003442348,0.002452678,0.00001038926,0.0001529776,0.000002496276,0.00007035889,0.00001058964,0.00005720421],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002598901,"threshold_uncertainty_score":0.4986818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01473997167789395,"score_gpt":0.2461698788004466,"score_spread":0.2314299071225526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}