{"id":"W2066827631","doi":"10.1016/j.cbpc.2011.09.011","title":"Sodium arsenite and cadmium chloride induction of proteasomal inhibition and HSP accumulation in Xenopus laevis A6 kidney epithelial cells","year":2011,"lang":"en","type":"article","venue":"Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"MG132; Ubiquitin; Proteasome; Sodium arsenite; Cadmium chloride; Xenopus; Proteasome inhibitor; Hsp70; Chemistry; Molecular biology; Cell biology; Biology; Cadmium; Biochemistry; Heat shock protein; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002726814,0.0004587194,0.0005332436,0.0005363242,0.0004187746,0.0005066603,0.0003615594,0.0003367503,0.001854512],"category_scores_gemma":[0.0001241536,0.0003540404,0.0007755273,0.0003877268,0.0003587667,0.000399357,0.0003309633,0.0008275231,0.0005570902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007357214,"about_ca_system_score_gemma":0.0005108782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004132309,"about_ca_topic_score_gemma":0.006232036,"domain_scores_codex":[0.9995852,0.00007289181,0.000075064,0.00006009221,0.00009637974,0.000110312],"domain_scores_gemma":[0.9998015,0.00004110861,0.00003780081,0.00003578178,0.00003942285,0.00004441942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001553846,0.00002550702,0.00008717317,0.00003283867,0.00000758681,0.00005136923,0.00002168941,0.00004452178,0.9991472,0.0001200127,0.00002884417,0.000277807],"study_design_scores_gemma":[0.000009145923,0.0001173133,0.001905118,0.000002286125,0.000007236427,0.00006406918,0.00003070176,0.0002364339,0.9966992,0.00001854141,0.0009054524,0.00000451901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923357,0.002196482,0.001612945,0.0001885875,0.00006228833,0.00004446468,0.0009812017,0.0001474994,0.002430729],"genre_scores_gemma":[0.9876878,0.001097057,0.001522156,0.00007150996,0.00001814988,0.00007011051,0.001191311,0.00003649046,0.008305499],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004132309,"threshold_uncertainty_score":0.0082165,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04325631959819901,"score_gpt":0.2979618275176385,"score_spread":0.2547055079194395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}