{"id":"W2066834513","doi":"10.1038/nrm2894","title":"The nuclear envelope in genome organization, expression and stability","year":2010,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":286,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Genome; Inner membrane; Biology; Genomic organization; Nuclear pore; Genetics; Computational biology; Cell biology; Nucleus; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006151478,0.0004505901,0.0009221299,0.00006775262,0.000161325,0.00004211594,0.0004536709,0.002487857,0.00004547271],"category_scores_gemma":[0.0004540254,0.0002738659,0.0002246247,0.0002924392,0.0001701888,0.000003332609,0.0003346371,0.001506979,0.00003167243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002771424,"about_ca_system_score_gemma":0.0001160081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000019969,"about_ca_topic_score_gemma":0.00001210194,"domain_scores_codex":[0.9975354,0.0006734194,0.0006143692,0.0007802485,0.00008209208,0.0003144646],"domain_scores_gemma":[0.9985428,0.00003414312,0.000382974,0.0008558685,0.00009913181,0.00008509015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001094844,0.0000261404,0.0000301057,0.002008597,0.00002721778,0.000004622894,0.0000158777,4.680349e-8,0.1587824,0.0002412063,0.0003739992,0.8384789],"study_design_scores_gemma":[0.0001150486,0.00006213387,0.00001065417,0.0002355632,0.00008360785,0.00002344344,0.000003424035,1.209104e-7,0.0007925141,0.00003627891,0.9983435,0.0002936765],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004695499,0.9972493,0.00004131064,0.00002862482,0.0004055631,0.0009902061,0.00001741709,0.00001119341,0.0007868559],"genre_scores_gemma":[0.000430017,0.997793,0.0005376272,0.0002394304,0.0002015012,0.00003120835,0.0006434236,0.00007970847,0.00004410954],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9979695,"threshold_uncertainty_score":0.9999713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007626985008499434,"score_gpt":0.2565570306227205,"score_spread":0.2489300456142211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}