{"id":"W2066858578","doi":"10.1126/science.1149590","title":"Comment on \"Tumor Growth Need Not Be Driven by Rare Cancer Stem Cells\"","year":2007,"lang":"en","type":"letter","venue":"Science","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec; Hôpital de l'Enfant-Jésus; University of Toronto; University Health Network","funders":"","keywords":"Cancer stem cell; Stem cell; Leukemia; Cancer research; Biology; Genetically engineered; Cancer; Genetically modified mouse; Genetically modified organism; Transgene; Immunology; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002642677,0.0009405858,0.001330376,0.0005462205,0.002311719,0.001745249,0.002095659,0.0405765,0.004452339],"category_scores_gemma":[0.01349285,0.0006934699,0.00103142,0.000606167,0.002545058,0.002300421,0.001017476,0.03403262,0.007982332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002955951,"about_ca_system_score_gemma":0.001635761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002641733,"about_ca_topic_score_gemma":0.003180372,"domain_scores_codex":[0.9979323,0.0005838809,0.0002781233,0.0003673129,0.0006026014,0.0002358037],"domain_scores_gemma":[0.9951461,0.00300033,0.0002942135,0.0001599407,0.0009708023,0.000428684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001191296,0.00003421327,0.0004988027,0.0000562129,0.00001576628,0.001346803,0.00007681956,0.00005292071,0.0003076104,0.00120214,0.9901962,0.006093289],"study_design_scores_gemma":[0.0003272858,0.0003252716,0.003133798,0.0003132803,0.0001005728,0.006161053,0.0005280458,0.0009628175,0.001861729,0.01025672,0.9758765,0.0001530349],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0006593912,0.00126113,0.0001557392,0.9737484,0.02255207,0.0000138788,0.00008510437,0.00006603177,0.001458156],"genre_scores_gemma":[0.003833446,0.000867788,0.0001904255,0.9677872,0.02415795,0.00003360886,0.00004199605,0.00002435715,0.003063264],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.0405765,"threshold_uncertainty_score":0.02144706,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03379350748725714,"score_gpt":0.2916303996310794,"score_spread":0.2578368921438223,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}