{"id":"W2066875072","doi":"10.1093/annonc/mdu336.49","title":"Prosper: a Phase 3 Study of Enzalutamide in Non-Metastatic (M0) Castration-Resistant Prostate Cancer (Crpc) Patients","year":2014,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Medicine; Prostate cancer; Enzalutamide; Internal medicine; Placebo; Oncology; Androgen receptor; Cancer; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002207276,0.00156097,0.002507053,0.0004559107,0.0005320383,0.0009950612,0.001019979,0.001376675,0.006337522],"category_scores_gemma":[0.001550545,0.0005807116,0.002127419,0.0004202425,0.001086699,0.00139304,0.0005749553,0.003324131,0.001047888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007893487,"about_ca_system_score_gemma":0.001766197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002188659,"about_ca_topic_score_gemma":0.008709486,"domain_scores_codex":[0.9994304,0.000346502,0.00002762463,0.00006435604,0.00004817604,0.00008302035],"domain_scores_gemma":[0.9993309,0.0001702921,0.0001341302,0.00004938598,0.00005295958,0.0002623629],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9102181,0.009299508,0.002054194,0.003152297,0.002224514,0.0001252561,0.0002317928,0.001814281,0.007351014,0.0005343213,0.006421114,0.05657368],"study_design_scores_gemma":[0.9315763,0.05922435,0.003952977,0.0001063974,0.0006224101,0.00009753313,0.00004563485,0.0003173236,0.0005231311,0.0002826678,0.00322452,0.00002669616],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9534762,0.01989202,0.001620321,0.002186337,0.0008118253,0.007904761,0.006395422,0.0004508597,0.007262309],"genre_scores_gemma":[0.9437634,0.01639762,0.00665121,0.003755569,0.000569904,0.008464596,0.008213242,0.0001837681,0.01200064],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006337522,"threshold_uncertainty_score":0.02120113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08478641429722598,"score_gpt":0.4556323950722166,"score_spread":0.3708459807749906,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}