{"id":"W2066890949","doi":"10.1038/sj.gt.3302319","title":"Reovirus as an experimental therapeutic for brain and leptomeningeal metastases from breast cancer","year":2004,"lang":"en","type":"article","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University; University of Calgary; Alberta Cancer Foundation","funders":"Canadian Institutes of Health Research; National Cancer Institute; Alberta Heritage Foundation for Medical Research; Health Research Board","keywords":"Breast cancer; In vivo; Oncolytic virus; Medicine; Cancer research; Metastasis; Cancer; Pathology; Immunology; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002334385,0.0002542775,0.0002040233,0.00005323508,0.0001755939,0.00005780362,0.0002545885,0.0001196841,0.0002011609],"category_scores_gemma":[0.00000441685,0.0002291181,0.00009448722,0.00007414799,0.0001381108,0.00001233088,0.00004778905,0.00007723925,0.000007036194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000044896,"about_ca_system_score_gemma":0.0001976574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004754414,"about_ca_topic_score_gemma":0.0002570104,"domain_scores_codex":[0.9985572,0.0001198667,0.00017062,0.0005638407,0.0001907907,0.0003977336],"domain_scores_gemma":[0.9992663,0.00001986403,0.00005787134,0.0004219277,0.00006467933,0.0001693417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007195368,0.0001858028,0.0001665321,0.000002056435,0.0002339823,0.000002483628,0.0003122998,0.00006676701,0.958899,0.00002873414,0.00009898355,0.032808],"study_design_scores_gemma":[0.00436345,0.004721933,0.0005330831,0.000005016236,0.00001149318,0.00002011615,0.0001670988,0.000009923021,0.9839562,0.000751483,0.005170231,0.0002899412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9785566,0.01901865,0.0002524363,0.0009488694,0.00009184046,0.0005148565,0.0005694301,0.00002791174,0.00001943972],"genre_scores_gemma":[0.9931188,0.00184901,0.0006589698,0.00297783,0.0005518381,0.0002961195,0.0003540178,0.00007621323,0.0001171992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03251806,"threshold_uncertainty_score":0.9343166,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03123200656406306,"score_gpt":0.3581118640713567,"score_spread":0.3268798575072936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}