{"id":"W2066929882","doi":"10.1016/j.bbrc.2003.12.030","title":"In vitro evolution of RNA aptamers recognizing carcinogenic aromatic amines","year":2003,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Deutsche Forschungsgemeinschaft","keywords":"In vitro; Carcinogen; Aptamer; RNA; Chemistry; Biochemistry; Computational biology; Biology; Molecular biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004048272,0.0001082439,0.0001769205,0.0001262633,0.0001070693,0.00001228106,0.0003102289,0.000125494,6.944709e-7],"category_scores_gemma":[0.0007208036,0.00009319325,0.00008241623,0.0005257067,0.000747707,0.00000689786,0.0002016459,0.0002307213,0.000001674215],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004809684,"about_ca_system_score_gemma":0.00005369051,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007260741,"about_ca_topic_score_gemma":0.00001295198,"domain_scores_codex":[0.9987404,0.0002834709,0.0002516383,0.0002713351,0.0001982067,0.0002549041],"domain_scores_gemma":[0.9988695,0.0001234548,0.00005772155,0.0007118653,0.0001507133,0.00008670482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003737678,0.0001841431,0.000100284,0.00001738065,0.00001682457,3.062713e-7,0.00001347896,5.609908e-8,0.9979293,0.0004675504,0.0001415335,0.001091733],"study_design_scores_gemma":[0.0001638168,0.00008902449,0.0002869041,0.0000286134,0.00001113705,0.000003160257,0.0001476425,0.0001186934,0.9958651,0.00206618,0.001109258,0.0001104712],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974172,0.001259894,0.0001257911,0.0005082363,0.000008564473,0.000147781,0.0000125175,0.000009852851,0.0005101243],"genre_scores_gemma":[0.9911122,0.0009033873,0.007771818,0.0000233397,0.00002848931,0.00002310223,0.00004757304,0.000009361672,0.00008066688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007646027,"threshold_uncertainty_score":0.380031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04570442876622819,"score_gpt":0.3573542993773688,"score_spread":0.3116498706111406,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}