{"id":"W2066929882","doi":"10.1016/j.bbrc.2003.12.030","title":"In vitro evolution of RNA aptamers recognizing carcinogenic aromatic amines","year":2003,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Deutsche Forschungsgemeinschaft","keywords":"In vitro; Carcinogen; Aptamer; RNA; Chemistry; Biochemistry; Computational biology; Biology; Molecular biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002986114,0.0003571766,0.0003101235,0.0001653783,0.0001720602,0.000393082,0.0003836193,0.0004661419,0.0009222364],"category_scores_gemma":[0.0004817393,0.0002488986,0.000380028,0.000141118,0.0002097425,0.0001735043,0.0002587718,0.000757634,0.0006209517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00042232,"about_ca_system_score_gemma":0.0001699474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009622282,"about_ca_topic_score_gemma":0.001666109,"domain_scores_codex":[0.9997755,0.00005650083,0.00001799397,0.00004070432,0.0000607956,0.00004852621],"domain_scores_gemma":[0.9997801,0.00008746346,0.00004362449,0.00002663926,0.00002342588,0.00003872615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004294466,0.0000185631,0.00005811039,0.00001218436,0.000004115913,0.00002879805,0.0000162448,0.0003642566,0.9985393,0.00008637385,0.00001441949,0.0008145166],"study_design_scores_gemma":[0.000006231099,0.00006675535,0.0002952463,0.000002057082,0.000009611034,0.00006756428,0.00001064717,0.001363264,0.997305,0.00002104615,0.0008481619,0.000004369299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842568,0.0003890354,0.01296657,0.00009832255,0.00006207333,0.00004947709,0.000187883,0.000207408,0.001782346],"genre_scores_gemma":[0.9871946,0.0002887704,0.008577758,0.00006845639,0.00001050923,0.00002312044,0.0004783237,0.0001034032,0.003255119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009622282,"threshold_uncertainty_score":0.003085196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04570442876622819,"score_gpt":0.3573542993773688,"score_spread":0.3116498706111406,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}