{"id":"W2066959425","doi":"10.1128/jvi.02468-08","title":"Proteasomal Degradation of the Papillomavirus E2 Protein Is Inhibited by Overexpression of Bromodomain-Containing Protein 4","year":2009,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research; Cancer Research Society; Northwestern University","keywords":"Biology; Luciferase; Transactivation; Bovine papillomavirus; Molecular biology; Ubiquitin; Transcription factor; Fusion protein; Transcription (linguistics); Cell biology; Transfection; Gene; Recombinant DNA; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000613233,0.0001469336,0.0002927646,0.00008685064,0.00005918514,0.000007083154,0.0003797207,0.0002318646,0.00003808471],"category_scores_gemma":[0.0001733089,0.0001024003,0.0001775267,0.0001388585,0.0001480013,0.00001192851,0.00007522086,0.0002823907,7.579646e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002433628,"about_ca_system_score_gemma":0.0001900964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001034877,"about_ca_topic_score_gemma":0.000004800497,"domain_scores_codex":[0.9982297,0.0004093404,0.0005879712,0.0001774516,0.0003588295,0.0002367448],"domain_scores_gemma":[0.9985093,0.0000132913,0.0008434106,0.0003237274,0.000242803,0.00006747354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006296105,0.0002002095,0.0004338683,0.0000178213,0.00005790684,0.000002404507,0.00005832784,0.00002115488,0.9887112,0.00002132751,0.0003925972,0.00378705],"study_design_scores_gemma":[0.001647795,0.01132168,0.001418009,0.0001208148,0.00001237847,0.00003425773,0.0000267595,0.00002527002,0.9843155,0.0004157982,0.0005707554,0.00009098528],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974535,0.000735616,0.0002338388,0.0008441674,0.0000223352,0.0006152854,0.00001669387,0.000002210865,0.00007636585],"genre_scores_gemma":[0.9989334,0.00002716229,0.0004666783,0.0002446965,0.00008312811,0.00001219694,0.000006178356,0.00001538068,0.0002112026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01112147,"threshold_uncertainty_score":0.4175763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01102957410458192,"score_gpt":0.2737293322588704,"score_spread":0.2626997581542885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}