{"id":"W2067082919","doi":"10.1097/00005344-200036051-00105","title":"Effects of a Selective Neutral Endopeptidase and a Nonselective Neutral Endopeptidase/Endothelin-Converting Enzyme Inhibitor on Lipopolysaccharide-Induced Endotoxaemia in Anaesthetized Sprague-Dawley Rats","year":2000,"lang":"en","type":"article","venue":"Journal of Cardiovascular Pharmacology","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Université de Sherbrooke","funders":"","keywords":"Neprilysin; Lipopolysaccharide; Internal medicine; Endocrinology; Endothelin receptor; Septic shock; Chemistry; Endothelins; Enzyme; Medicine; Receptor; Sepsis; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000407652,0.0008951955,0.0006936683,0.0004452439,0.0001904199,0.0002389829,0.0003433209,0.0004676725,0.001263573],"category_scores_gemma":[0.0003663628,0.0003259821,0.000593395,0.0002089076,0.0005258897,0.0003656604,0.0002723781,0.001251984,0.000245239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000191693,"about_ca_system_score_gemma":0.0004978459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007724948,"about_ca_topic_score_gemma":0.001375989,"domain_scores_codex":[0.9997302,0.00005793823,0.00003632594,0.00004332914,0.00004948371,0.00008280168],"domain_scores_gemma":[0.9995161,0.00007053281,0.0001229848,0.00004041877,0.00004269773,0.0002073005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01607775,0.001936422,0.0004233947,0.0001379669,0.00005864775,0.0002017256,0.00006521698,0.0001762517,0.9752275,0.0001282588,0.0001205081,0.005446439],"study_design_scores_gemma":[0.002128075,0.05799516,0.01012719,0.00002924875,0.0002379222,0.0003650087,0.0001427708,0.001542032,0.9252732,0.0001251667,0.00199051,0.00004368684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971995,0.0009957943,0.0007922562,0.0001407613,0.00007898515,0.00005473699,0.0002115868,0.00005408949,0.0004723581],"genre_scores_gemma":[0.9920713,0.001982479,0.002776563,0.0001762767,0.00007747109,0.0001500056,0.0006145185,0.00002272369,0.002128581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001263573,"threshold_uncertainty_score":0.004227042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01939671718714767,"score_gpt":0.2940825627982529,"score_spread":0.2746858456111052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}