{"id":"W2067089684","doi":"10.1097/tp.0b013e3181b47cfa","title":"Dissociation Between Peripheral Blood Chimerism and Tolerance to Hindlimb Composite Tissue Transplants: Preferential Localization of Chimerism in Donor Bone","year":2009,"lang":"en","type":"article","venue":"Transplantation","topic":"Organ and Tissue Transplantation Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Particle Physics","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; University of Louisville","keywords":"Total body irradiation; Bone marrow; Chimera (genetics); Haematopoiesis; Immunology; Medicine; Transplantation; Transplantation Chimera; Monoclonal antibody; Immune tolerance; Antibody; Immune system; Biology; Stem cell; Internal medicine; Chemotherapy; Hematopoietic cell; Cyclophosphamide; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001660074,0.000197896,0.0004370225,0.0002849389,0.00007329396,0.00002425736,0.00006576408,0.0001446985,0.00007509209],"category_scores_gemma":[0.000005371739,0.0002027934,0.00004318389,0.000383187,0.00004270393,0.0001965887,0.000002305903,0.0001915234,0.000007484591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003099725,"about_ca_system_score_gemma":0.00003860353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001741572,"about_ca_topic_score_gemma":0.0001250161,"domain_scores_codex":[0.9983766,0.00009278394,0.0005392037,0.0003222646,0.0003974253,0.0002716983],"domain_scores_gemma":[0.9995008,0.00004613385,0.00009396928,0.0001248151,0.00007035119,0.0001639532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004535629,0.0009305988,0.4678711,0.001808115,0.0001696052,0.0001467001,0.0262754,0.001030702,0.4702269,0.0002661413,0.00002195728,0.02671713],"study_design_scores_gemma":[0.005101518,0.0007331775,0.8656078,0.0004303548,0.0003078879,0.00005142071,0.00005293199,0.0003391097,0.1270876,0.00005736415,0.00003804838,0.0001927923],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.97547,0.0001894255,0.02220355,0.0007564439,0.00004699126,0.0008300598,0.0001763798,0.00005356918,0.0002735535],"genre_scores_gemma":[0.9968067,0.0008154173,0.001029472,0.0001296525,0.00009453676,0.00001437777,0.00098881,0.00002078791,0.0001002706],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3977367,"threshold_uncertainty_score":0.8269675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01245030801175896,"score_gpt":0.2954807276277379,"score_spread":0.2830304196159789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}