{"id":"W2067193667","doi":"10.4049/jimmunol.169.12.7026","title":"Hydrogen Peroxide Induces Murine Macrophage Chemokine Gene Transcription Via Extracellular Signal-Regulated Kinase- and Cyclic Adenosine 5′-Monophosphate (cAMP)-Dependent Pathways: Involvement of NF-κB, Activator Protein 1, and cAMP Response Element Binding Protein","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"CREB; Chemokine; Cell biology; Protein kinase A; MAPK/ERK pathway; Molecular biology; Chemistry; Signal transduction; Biology; Transcription factor; Kinase; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001701767,0.0005877707,0.0002620824,0.0002331568,0.0001288564,0.0002052535,0.0001312738,0.0002336289,0.001385903],"category_scores_gemma":[0.0000759895,0.0001824381,0.0003055592,0.0001320458,0.0002491688,0.0001743053,0.0001740046,0.0003786097,0.0003071003],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002708686,"about_ca_system_score_gemma":0.000175688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000444202,"about_ca_topic_score_gemma":0.0009321496,"domain_scores_codex":[0.999867,0.00002237962,0.000007257849,0.00002129641,0.00002934905,0.00005275419],"domain_scores_gemma":[0.9999092,0.00001364736,0.0000292105,0.000007801835,0.00001203392,0.00002813401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002177055,0.00004110673,0.0001035274,0.00005175972,0.000003734452,0.00003117781,0.00001144162,0.00001184646,0.9989078,0.00002095302,0.00002625525,0.0005726992],"study_design_scores_gemma":[0.00007539878,0.001385925,0.01284048,0.00001421336,0.00002927754,0.0002785184,0.00004632315,0.0004577551,0.9821336,0.00008213978,0.002647159,0.00000920233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917461,0.004993212,0.001569113,0.0001183793,0.00006104029,0.00005546688,0.0003203551,0.00007059342,0.001065752],"genre_scores_gemma":[0.989489,0.003253886,0.002534759,0.0001400672,0.00005450341,0.0001571209,0.0008316046,0.00001963603,0.003519421],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001385903,"threshold_uncertainty_score":0.004636288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01416180484691815,"score_gpt":0.1989751075511568,"score_spread":0.1848133027042387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}