{"id":"W2067197352","doi":"10.1016/j.vaccine.2007.10.040","title":"Genomic differences of Vaccinia virus clones from Dryvax smallpox vaccine: The Dryvax-like ACAM2000 and the mouse neurovirulent Clone-3","year":2007,"lang":"en","type":"article","venue":"Vaccine","topic":"Poxvirus research and outbreaks","field":"Immunology and Microbiology","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Vaccinia; Virology; Biology; Smallpox vaccine; Modified vaccinia Ankara; Smallpox virus; clone (Java method); Cowpox virus; Orthopoxvirus; Population; Virus; Genetics; Gene; Recombinant DNA; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001075294,0.0003791758,0.000656242,0.00015988,0.000448567,0.00005067119,0.0009468172,0.0002775196,0.001016766],"category_scores_gemma":[0.0002090843,0.0001969982,0.0001807662,0.0002490661,0.000149579,0.0001013726,0.0005047415,0.0007565678,0.0002985714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003007949,"about_ca_system_score_gemma":0.00007115218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005115435,"about_ca_topic_score_gemma":0.002245484,"domain_scores_codex":[0.9973669,0.0004952299,0.0007259079,0.0005073064,0.000122057,0.000782595],"domain_scores_gemma":[0.9970347,0.001664956,0.0002805248,0.000833429,0.00009902157,0.00008741982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00794896,0.000225719,0.05926896,0.00002349438,0.0006065257,0.00001841859,0.001337068,0.000002035825,0.9065452,0.0008701456,0.007146872,0.01600656],"study_design_scores_gemma":[0.008538119,0.0004268101,0.739185,0.00002439326,0.0001897976,0.00005600048,0.0004238172,0.0000236039,0.2070542,0.0006253075,0.04308041,0.0003724774],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.978424,0.01813815,0.00004475862,0.001693471,0.0004440436,0.0006006784,0.000186243,0.00006717534,0.0004014949],"genre_scores_gemma":[0.9912857,0.005546478,0.00002323763,0.0008728214,0.0001686088,0.00002780729,0.00007474896,0.00003629748,0.001964252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.699491,"threshold_uncertainty_score":0.9998965,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01204605122926101,"score_gpt":0.2388431519338004,"score_spread":0.2267971007045394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}