{"id":"W2067241131","doi":"10.1111/epi.12660","title":"Once‐daily <scp>USL</scp>255 as adjunctive treatment of partial‐onset seizures: Randomized phase <scp>III</scp> study","year":2014,"lang":"en","type":"article","venue":"Epilepsia","topic":"Epilepsy research and treatment","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Florida Health; H. Lundbeck A/S; Upsher-Smith; Valeant Pharmaceuticals International; Sunovion; Florida Department of Health","keywords":"Adverse effect; Placebo; Medicine; Clinical Global Impression; Randomized controlled trial; Refractory (planetary science); Quality of life (healthcare); Topiramate; Internal medicine; Adjunctive treatment; Anesthesia; Neurocognitive; Lennox–Gastaut syndrome; Epilepsy; Psychiatry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001209941,0.00104183,0.001625143,0.000327264,0.0002415218,0.0006054403,0.0006906744,0.0008383372,0.00512618],"category_scores_gemma":[0.0006006953,0.0003727965,0.001000018,0.0003664947,0.0006273321,0.0003940563,0.0001968549,0.001336135,0.0007555176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000620171,"about_ca_system_score_gemma":0.00132603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001275094,"about_ca_topic_score_gemma":0.004572084,"domain_scores_codex":[0.999757,0.0001254031,0.00001748558,0.00003308331,0.0000344544,0.00003259999],"domain_scores_gemma":[0.9995874,0.00008187637,0.000116317,0.0000295416,0.00003508687,0.0001498845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9081852,0.01394703,0.002099473,0.002008494,0.001893623,0.0001488148,0.00007326173,0.0007376514,0.01727146,0.0001919616,0.00301022,0.0504328],"study_design_scores_gemma":[0.8922533,0.09939039,0.004725989,0.00005902969,0.000513094,0.0001091495,0.00001678171,0.00043179,0.001278379,0.00007188482,0.001138203,0.0000119137],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857206,0.004187165,0.000643593,0.0003586421,0.0001545627,0.004825335,0.001678096,0.0001687719,0.002263139],"genre_scores_gemma":[0.984614,0.004041992,0.001588103,0.001027676,0.0002301243,0.003341719,0.00206907,0.00002780957,0.003059523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00512618,"threshold_uncertainty_score":0.01714879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02481030017861867,"score_gpt":0.3356410226671141,"score_spread":0.3108307224884954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}