{"id":"W2067258891","doi":"10.1038/srep01350","title":"Collapsin response mediator protein 3 deacetylates histone H4 to mediate nuclear condensation and neuronal death","year":2013,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; National Research Council Canada","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Histone deacetylase 5; Histone; HDAC11; Excitotoxicity; Biology; Histone H4; Histone deacetylase; Cell biology; Acetylation; HDAC10; Mediator; Histone deacetylase 2; Neuroprotection; Chemistry; Programmed cell death; Apoptosis; Biochemistry; Neuroscience; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001346723,0.0001992805,0.0002088033,0.0002299983,0.0005978728,0.0004442833,0.0001844538,0.00007035257,0.0004494617],"category_scores_gemma":[0.002693569,0.000181986,0.00005145412,0.0005089044,0.0003158408,0.0004458014,0.000159314,0.0001558731,0.000395776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007393683,"about_ca_system_score_gemma":0.0001578088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002501677,"about_ca_topic_score_gemma":0.000003880044,"domain_scores_codex":[0.9967944,0.0002608382,0.0005262394,0.001138315,0.0008349017,0.000445328],"domain_scores_gemma":[0.9984535,0.0002307682,0.0002782085,0.000513098,0.0001385426,0.0003858617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008537572,0.00003065911,0.0003003547,0.000008530177,0.000001350089,0.000154121,0.0003961377,0.00001569633,0.9934977,0.0001097464,0.005079689,0.0003205831],"study_design_scores_gemma":[0.0001854996,0.0001389985,0.004951272,0.00003649732,0.000007522631,0.0001777248,0.00005751367,0.0003085528,0.9668989,0.003376067,0.02359453,0.0002669083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994803,0.00003687226,0.00001801657,0.0017107,0.002035011,0.001017193,0.000003752091,0.0001341504,0.0002412836],"genre_scores_gemma":[0.9948118,0.000002788307,0.0003245153,0.0007285943,0.00006867485,0.00008432403,0.00000256666,0.00003424799,0.003942506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02659884,"threshold_uncertainty_score":0.7421173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02494868358049203,"score_gpt":0.2654736983203843,"score_spread":0.2405250147398922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}