{"id":"W2067264214","doi":"10.1021/ac048672l","title":"Impedance Sensing of DNA Binding Drugs Using Gold Substrates Modified with Gold Nanoparticles","year":2004,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":199,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"Chemistry; Colloidal gold; Nanoparticle; DNA; Nanotechnology; Electrical impedance; Combinatorial chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001296268,0.0002301522,0.0002854748,0.00003034575,0.00005101499,0.00002690059,0.0001394913,0.000182464,0.000001214262],"category_scores_gemma":[0.00005993187,0.0001916878,0.0001363324,0.0002756918,0.000308017,0.000008247385,0.00006575672,0.0001254711,7.793387e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004333444,"about_ca_system_score_gemma":0.00009246835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002827136,"about_ca_topic_score_gemma":0.000006414484,"domain_scores_codex":[0.9986821,0.00001459526,0.0003195742,0.0004355,0.0002096702,0.0003385776],"domain_scores_gemma":[0.999182,0.00001578568,0.0001584715,0.0003829125,0.0001428843,0.000117971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007733867,0.0000529219,0.0002217663,0.00004360743,0.00009350491,0.00001222454,0.00001288924,0.000425067,0.9986545,0.00003388067,0.00001768933,0.0003546164],"study_design_scores_gemma":[0.0003828802,0.0000659154,0.00002453604,0.00009972594,0.0001226048,0.00004655871,0.0001575048,0.001338499,0.997306,0.0001414931,0.00004531387,0.0002689511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979475,0.00008696669,0.0009169124,0.0000623472,0.000008555274,0.00005450673,0.00001230241,0.00003821887,0.0008726911],"genre_scores_gemma":[0.9927263,0.00003561918,0.006806718,0.00004386951,0.00009975745,7.197625e-7,0.00003759409,0.00002536118,0.0002240908],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005889805,"threshold_uncertainty_score":0.78168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01407914488402457,"score_gpt":0.2690514691436872,"score_spread":0.2549723242596626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}