{"id":"W2067281577","doi":"10.1021/bi700265j","title":"Peptide Binding by a Fragment of Calmodulin Composed of EF-Hands 2 and 3","year":2007,"lang":"en","type":"article","venue":"Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Calmodulin; Tetramer; Peptide; Biophysics; Allosteric regulation; Crystallography; Stereochemistry; Biochemistry; Receptor; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000213133,0.0001232301,0.0001471114,0.00001761425,0.00002353606,0.000003980493,0.0001358473,0.0001477705,0.0000196575],"category_scores_gemma":[0.00008490183,0.0001290038,0.0000652379,0.00006004214,0.0001502724,0.000001026534,0.00009225805,0.00005158468,8.280459e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001148753,"about_ca_system_score_gemma":0.0000453152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008113134,"about_ca_topic_score_gemma":5.247479e-7,"domain_scores_codex":[0.9991755,0.00001040188,0.0002598382,0.000247218,0.0001381513,0.0001688427],"domain_scores_gemma":[0.9994011,0.00001959295,0.0001377652,0.0002722979,0.00006111716,0.0001081562],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000127512,0.00009837709,0.008659876,0.0001389431,0.00004093827,0.000002560115,0.00002052842,0.00000234678,0.9885361,0.000002457296,0.002079253,0.000291122],"study_design_scores_gemma":[0.000742127,0.0001079299,0.0004059199,0.00004850372,0.00001968887,0.000005725903,0.00006968016,0.000009266829,0.9979455,0.00000609966,0.0005111244,0.0001283922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974312,0.001280318,0.0003591104,0.00001210985,0.00003080081,0.00006684263,0.0001016634,0.000005608939,0.000712397],"genre_scores_gemma":[0.9987518,0.00002431984,0.0005841558,0.00002743041,0.00006651261,0.000002913583,0.0001598017,0.00001432333,0.0003687748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009409455,"threshold_uncertainty_score":0.5260623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005728296034790426,"score_gpt":0.2387203284296296,"score_spread":0.2329920323948392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}