{"id":"W2067347462","doi":"10.1016/j.taap.2007.10.021","title":"Cigarette smoke decreases mitochondrial porin expression and steroidogenesis","year":2007,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Florida Department of Health","keywords":"Pregnenolone; Voltage-dependent anion channel; Steroidogenic acute regulatory protein; Mitochondrion; Cholesterol side-chain cleavage enzyme; Porin; Chemistry; Inner mitochondrial membrane; Cell biology; Cell fractionation; Internal medicine; Hormone; Biology; Biochemistry; Endocrinology; Steroid; Messenger RNA; Bacterial outer membrane; Membrane; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001581805,0.0003315586,0.0003874645,0.0002877201,0.0003022922,0.0005429912,0.0002645401,0.0004732145,0.002811661],"category_scores_gemma":[0.0002667809,0.0003439606,0.0003490349,0.0001963022,0.0005168609,0.0003827406,0.000284417,0.0008859112,0.0004572861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003537946,"about_ca_system_score_gemma":0.0003837488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001497858,"about_ca_topic_score_gemma":0.002437493,"domain_scores_codex":[0.9997676,0.00003874477,0.00001378167,0.00004844422,0.00005297115,0.00007847437],"domain_scores_gemma":[0.9996137,0.00006443357,0.00007341392,0.00006844914,0.0000371572,0.0001428855],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001292745,0.0001092502,0.00142229,0.00001993128,0.00001216932,0.00006210816,0.00002621846,0.00001899731,0.9950465,0.0001503318,0.00006035209,0.001779138],"study_design_scores_gemma":[0.00003056399,0.0005337159,0.0342112,0.000006276909,0.00003677342,0.0002829684,0.0001384932,0.0003174867,0.9632144,0.0001468155,0.001074884,0.000006501326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953951,0.001680205,0.001191446,0.0003543861,0.00008142552,0.00001041882,0.0002342121,0.000110152,0.0009426529],"genre_scores_gemma":[0.9933259,0.0007399765,0.0003572215,0.0000914081,0.00002321506,0.00001135695,0.0003314874,0.00002895765,0.005090472],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002811661,"threshold_uncertainty_score":0.009405971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01628269971428151,"score_gpt":0.2807062444852848,"score_spread":0.2644235447710032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}