{"id":"W2067352199","doi":"10.1161/hypertensionaha.114.03179","title":"Flaxseed Consumption Reduces Blood Pressure in Patients With Hypertension by Altering Circulating Oxylipins via an α-Linolenic Acid–Induced Inhibition of Soluble Epoxide Hydrolase","year":2014,"lang":"en","type":"article","venue":"Hypertension","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Research Manitoba; St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"Epoxide hydrolase 2; Chemistry; Epoxide hydrolase; Blood pressure; alpha-Linolenic acid; Biochemistry; Polyunsaturated fatty acid; Fatty acid; Internal medicine; Endocrinology; Pharmacology; Enzyme; Medicine; Docosahexaenoic acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000275812,0.000304967,0.0004469836,0.0001298947,0.000141828,0.00001946675,0.0001291063,0.000324356,0.00001475192],"category_scores_gemma":[0.00006858251,0.0002653384,0.00007683192,0.0001142675,0.00008054897,0.00003506001,0.0001165421,0.0002080051,0.000004743529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009573038,"about_ca_system_score_gemma":0.00003267603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009813447,"about_ca_topic_score_gemma":0.00004266158,"domain_scores_codex":[0.9979189,0.000220753,0.0004930673,0.0006952225,0.0002771009,0.0003949597],"domain_scores_gemma":[0.9988286,0.00002353538,0.0002716457,0.0004302349,0.0002939966,0.0001519189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000427648,0.0006751919,0.0108701,0.00004956834,0.00007118671,0.000008411036,0.00002701173,0.0002739347,0.9858738,0.000002660199,0.0002508433,0.001469699],"study_design_scores_gemma":[0.005430195,0.001631065,0.02713071,0.0001452574,0.0002613768,0.000057597,0.00001906409,0.008508959,0.9561018,0.00001097035,0.0003064997,0.000396548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986436,0.0004176537,0.0001691876,0.00005154771,0.0002630108,0.0003805567,0.00001241897,0.00003391713,0.00002806193],"genre_scores_gemma":[0.9982366,0.00006332593,0.0004864663,0.0004749683,0.0001051228,0.00002005602,0.0005350377,0.0000560585,0.00002235683],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02977199,"threshold_uncertainty_score":0.9999799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0136786618650028,"score_gpt":0.2218537448151258,"score_spread":0.208175082950123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}