{"id":"W2067394538","doi":"10.1182/blood-2006-01-029199","title":"Phospholipase C, calcium, and calmodulin are critical for α4β1 integrin affinity up-regulation and monocyte arrest triggered by chemoattractants","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Monocyte; Calmodulin; Calcium; Integrin; Chemotaxis; Cell biology; Immunology; Chemistry; Receptor; Internal medicine; Medicine; Endocrinology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001215755,0.0003486373,0.000236719,0.0002181526,0.000248384,0.0003414555,0.0001723394,0.0003732985,0.001843428],"category_scores_gemma":[0.0001810443,0.0001877405,0.0002025971,0.0001299057,0.0001983805,0.0002111714,0.0002358222,0.0004322368,0.0003397412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005466463,"about_ca_system_score_gemma":0.0002757115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007822392,"about_ca_topic_score_gemma":0.001172105,"domain_scores_codex":[0.9998097,0.00002830471,0.00001261639,0.00002912129,0.00003870648,0.00008158775],"domain_scores_gemma":[0.9998811,0.00001517888,0.00003995682,0.000008691446,0.00001759292,0.00003737786],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002208854,0.00001778092,0.0001673318,0.00002815383,0.000002170732,0.00005358968,0.000007384497,0.00001200578,0.9989021,0.00006598191,0.0000344634,0.0004881199],"study_design_scores_gemma":[0.0001399814,0.0002966966,0.03121566,0.00002027232,0.00002692709,0.0004569151,0.00005915236,0.001377443,0.9614609,0.0001868703,0.004750812,0.00000838463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922432,0.003325507,0.001726275,0.0002823421,0.00005957573,0.00008332018,0.0003689468,0.00004798256,0.001862846],"genre_scores_gemma":[0.9946149,0.0009760503,0.001311909,0.00009105936,0.00002899815,0.0001237564,0.0004648591,0.00001049547,0.002377988],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001843428,"threshold_uncertainty_score":0.006166875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03130219160038489,"score_gpt":0.3191470580660539,"score_spread":0.287844866465669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}