{"id":"W2067400755","doi":"10.1089/10799900152547876","title":"Induction of Collagenase mRNA Expression in Dermal Fibroblasts by IFN- <i>α</i> 2b and Determination of the IFN- <i>α</i> 2b Responsive Element on 5′-Flanking Regions of Collagenase Promoter","year":2001,"lang":"en","type":"article","venue":"Journal of Interferon & Cytokine Research","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Sick Kids Foundation","keywords":"Collagenase; Molecular biology; Messenger RNA; Interstitial collagenase; Gene expression; Transcription (linguistics); Chemistry; Biology; Gene; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001953349,0.0001530012,0.0003095198,0.0003921471,0.00008451954,0.0000144234,0.0003924377,0.0002206238,0.0000204321],"category_scores_gemma":[0.0005512814,0.0001089941,0.0001254139,0.0004164201,0.0003596529,0.00001859543,0.0003085444,0.000444057,4.632753e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007853963,"about_ca_system_score_gemma":0.0002496383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002480932,"about_ca_topic_score_gemma":0.00006839954,"domain_scores_codex":[0.9970294,0.001018349,0.0007239928,0.0002581113,0.0006401276,0.0003299842],"domain_scores_gemma":[0.9980801,0.0001632107,0.0004796687,0.0003503995,0.0008275599,0.00009901676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004655661,0.0003327221,0.002546318,0.00007735522,0.00003671016,0.00004130137,0.0002223317,0.00001885647,0.9873133,0.000005806928,0.002537359,0.002212227],"study_design_scores_gemma":[0.001543523,0.003923883,0.001957937,0.0006439881,0.00001059023,0.000250449,0.0005383528,0.00005525315,0.9894295,0.00003840352,0.00152038,0.00008768647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978541,0.0006347141,0.0002556459,0.0005468458,0.00006683032,0.000409338,0.00002603204,0.000001133934,0.0002054087],"genre_scores_gemma":[0.9985421,0.0008211833,0.000132151,0.00002415952,0.00009016458,0.00001129924,0.00001396065,0.00001804265,0.0003468794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003591161,"threshold_uncertainty_score":0.4444649,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02877342269608189,"score_gpt":0.3280641884201331,"score_spread":0.2992907657240512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}