{"id":"W2067400755","doi":"10.1089/10799900152547876","title":"Induction of Collagenase mRNA Expression in Dermal Fibroblasts by IFN- α 2b and Determination of the IFN- α 2b Responsive Element on 5′-Flanking Regions of Collagenase Promoter","year":2001,"lang":"en","type":"article","venue":"Journal of Interferon & Cytokine Research","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Sick Kids Foundation","keywords":"Collagenase; Molecular biology; Messenger RNA; Interstitial collagenase; Gene expression; Transcription (linguistics); Chemistry; Biology; Gene; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003324508,0.0004195999,0.0003488001,0.0002309551,0.0001705407,0.0003271848,0.0001462104,0.0002415287,0.001601448],"category_scores_gemma":[0.0001898425,0.0002642431,0.0004020032,0.0002330134,0.0002998773,0.0001420957,0.0001564655,0.0008521712,0.0006312046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004393786,"about_ca_system_score_gemma":0.0002212524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001081346,"about_ca_topic_score_gemma":0.001726651,"domain_scores_codex":[0.9995927,0.00008210701,0.00004003951,0.0001087447,0.0001080205,0.00006830932],"domain_scores_gemma":[0.9997495,0.00008198201,0.00006228268,0.0000301725,0.00004058729,0.00003535555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003627351,0.000008181783,0.00004303611,0.00001092094,8.074182e-7,0.00000587157,0.000007401719,0.00001355758,0.999707,0.000008989307,0.000004938212,0.0001529257],"study_design_scores_gemma":[0.000009029675,0.0001548309,0.002665617,0.000005736448,0.000004662232,0.00006052299,0.00002074016,0.0004551921,0.9959247,0.00001312075,0.0006826457,0.000003261838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9764131,0.003213328,0.0156625,0.0001401552,0.00008309761,0.0001319085,0.002001593,0.0001120347,0.002242244],"genre_scores_gemma":[0.9538428,0.002418064,0.02845373,0.0001788242,0.00005087806,0.0004020641,0.004708557,0.0000870633,0.009858042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001601448,"threshold_uncertainty_score":0.005357385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02877342269608189,"score_gpt":0.3280641884201331,"score_spread":0.2992907657240512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}