{"id":"W2067423114","doi":"10.1021/tx049756s","title":"Evidence of Hemoglobin Binding to Arsenic as a Basis for the Accumulation of Arsenic in Rat Blood","year":2004,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Arsenic contamination and mitigation","field":"Environmental Science","cited_by":165,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Arsenic; Chemistry; Hemoglobin; Arsenite; Phenylarsine oxide; Biochemistry; Arsenic toxicity; In vivo; Arsenate; Cysteine; Stereochemistry; Enzyme; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000125334,0.0001888614,0.0001077391,0.000295248,0.00009017267,0.0001386204,0.000129955,0.0001676262,0.001134167],"category_scores_gemma":[0.000133271,0.0001265,0.0001296119,0.0001752419,0.0001716787,0.00007351075,0.0001035421,0.0002080483,0.0002503423],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001630545,"about_ca_system_score_gemma":0.0001482548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001954584,"about_ca_topic_score_gemma":0.00155909,"domain_scores_codex":[0.999943,0.00001401992,0.00000291997,0.00001340068,0.00001369562,0.0000129772],"domain_scores_gemma":[0.9998873,0.00002319692,0.00002701054,0.00001304557,0.0000272717,0.00002209297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001777082,0.000009084599,0.001024761,0.00002093847,0.000007543862,0.00004152307,0.00001925148,0.00002038504,0.9973169,0.00007320027,0.00002722059,0.001261493],"study_design_scores_gemma":[0.00001684675,0.0008127492,0.05248312,0.000008479866,0.00005661555,0.0006772861,0.00006662049,0.0009167037,0.9431146,0.000108012,0.001731416,0.000007504875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929812,0.001439907,0.003896079,0.00009674519,0.0000186935,0.00001033067,0.0001629403,0.0001200938,0.001274007],"genre_scores_gemma":[0.9939022,0.001107826,0.002529723,0.00007161805,0.00001140322,0.00001399302,0.0002526397,0.00001597849,0.002094616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001954584,"threshold_uncertainty_score":0.003886342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.196705211361736,"score_gpt":0.4453187701240206,"score_spread":0.2486135587622846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}