{"id":"W2067496779","doi":"10.2174/13892010113146660230","title":"Challenges and Opportunities for Bacterial Vaccine Development in the 21<sup>st</sup> Century","year":2014,"lang":"en","type":"review","venue":"Current Pharmaceutical Biotechnology","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research Manitoba","funders":"","keywords":"Proteomics; Informatics; Genomics; Computational biology; Biology; Biotechnology; Bioinformatics; Genome; Political science; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001573435,0.0006635329,0.0009839672,0.001376401,0.0004501804,0.001940953,0.0007074596,0.002338219,0.004799212],"category_scores_gemma":[0.001158902,0.0002952438,0.000495146,0.001734514,0.0009051645,0.002913438,0.001050017,0.002815736,0.003510558],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009913218,"about_ca_system_score_gemma":0.002551904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001146732,"about_ca_topic_score_gemma":0.001692178,"domain_scores_codex":[0.9996262,0.00009076439,0.0000342447,0.00004766636,0.0001567894,0.00004439948],"domain_scores_gemma":[0.9994147,0.0002968465,0.00005927041,0.00002092512,0.0001380862,0.0000702361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005551151,0.00008706807,0.000148461,0.009485485,0.0000403404,0.0001943777,0.0001475278,0.0006496089,0.003905946,0.02915017,0.03343669,0.9226988],"study_design_scores_gemma":[0.000005531562,0.00005363208,0.0001971519,0.00178324,0.00001873682,0.0003691419,0.0001149231,0.0001041369,0.0004651584,0.006725514,0.990151,0.00001185425],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002081415,0.9945441,0.0005615758,0.002293837,0.0004014125,0.000005212772,0.000013654,0.00001340834,0.001958521],"genre_scores_gemma":[0.001247704,0.9949414,0.001025568,0.0008695723,0.0003170976,0.000008961048,0.00002737396,0.000004335148,0.001557963],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004799212,"threshold_uncertainty_score":0.01605499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1525293524953344,"score_gpt":0.3573047215792921,"score_spread":0.2047753690839577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}