{"id":"W2067533175","doi":"10.1016/s2213-8587(14)70174-3","title":"Efficacy and safety of a fixed-ratio combination of insulin degludec and liraglutide (IDegLira) compared with its components given alone: results of a phase 3, open-label, randomised, 26-week, treat-to-target trial in insulin-naive patients with type 2 diabetes","year":2014,"lang":"en","type":"article","venue":"The Lancet Diabetes & Endocrinology","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":362,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Novo Nordisk","keywords":"Insulin degludec; Liraglutide; Medicine; Metformin; Type 2 diabetes; Insulin; Pioglitazone; Clinical endpoint; Internal medicine; Diabetes mellitus; Urology; Endocrinology; Insulin glargine; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002008789,0.001953421,0.004256943,0.0005814906,0.0003234303,0.00153615,0.001356417,0.001873833,0.004979096],"category_scores_gemma":[0.002204153,0.001001207,0.002674866,0.0005320825,0.00132071,0.002072919,0.0005217586,0.004227049,0.001100502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000992189,"about_ca_system_score_gemma":0.0007341711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009869359,"about_ca_topic_score_gemma":0.00146871,"domain_scores_codex":[0.9991348,0.0004405237,0.00006233979,0.0001744627,0.00006387403,0.0001240597],"domain_scores_gemma":[0.9990121,0.0003561287,0.0002129566,0.00009138328,0.00004038702,0.000287055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9845513,0.003239553,0.0003101023,0.0001862767,0.0005604263,0.00001500397,0.00002099541,0.0002188672,0.001596408,0.00002586389,0.0001673512,0.009107841],"study_design_scores_gemma":[0.9015938,0.09468457,0.001640935,0.00002052485,0.0007535903,0.000036078,0.00002526989,0.0005304076,0.0004421137,0.00007800076,0.0001734205,0.00002127896],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927486,0.004099245,0.0003906309,0.0003423762,0.0002828509,0.0004622985,0.0004109751,0.000122286,0.001140854],"genre_scores_gemma":[0.9940303,0.001890755,0.00110157,0.0004687169,0.0003120568,0.0004964241,0.0005759958,0.00003685619,0.001087276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004979096,"threshold_uncertainty_score":0.01665676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03207177693034416,"score_gpt":0.2833180045613597,"score_spread":0.2512462276310156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}