{"id":"W2067571605","doi":"10.1016/j.smim.2012.05.001","title":"Activation induced deaminase: How much and where?","year":2012,"lang":"en","type":"review","venue":"Seminars in Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"Canada Research Chairs; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Activation-induced (cytidine) deaminase; Biology; Somatic hypermutation; Cell biology; Immunoglobulin class switching; Cytidine deaminase; Epigenetics; Computational biology; Gene; Genetics; B cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000787119,0.00120308,0.002079306,0.0008561021,0.0002609757,0.001681752,0.001285367,0.002212469,0.002146652],"category_scores_gemma":[0.0006689013,0.0003282996,0.0003907189,0.001289354,0.001198729,0.002342054,0.0007356562,0.003130849,0.002985661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00102947,"about_ca_system_score_gemma":0.001432485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007394388,"about_ca_topic_score_gemma":0.001140046,"domain_scores_codex":[0.9998125,0.00003167406,0.00003121179,0.00004541099,0.00004635179,0.00003276562],"domain_scores_gemma":[0.9996794,0.0001169445,0.00005183409,0.00001562326,0.00008011747,0.00005611319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001813343,0.00005369759,0.0001747331,0.007080681,0.00006245512,0.0002816194,0.00003777535,0.0002649877,0.003429449,0.004492905,0.05345126,0.9304891],"study_design_scores_gemma":[0.00003023954,0.0000624137,0.00043485,0.001407525,0.0000817034,0.001369079,0.00007024203,0.0000776922,0.001464777,0.003516594,0.9914619,0.00002311221],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009168375,0.9972929,0.0002417744,0.0008509005,0.0008805073,0.000001924634,0.00001250622,0.000009386804,0.0006184414],"genre_scores_gemma":[0.00111267,0.9961147,0.0003147553,0.0006732821,0.0008317865,0.00000584704,0.00003275602,0.000003140342,0.0009110649],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002212469,"threshold_uncertainty_score":0.007469416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03128470113934409,"score_gpt":0.2758584273700201,"score_spread":0.2445737262306761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}