{"id":"W2067573216","doi":"10.1016/j.eururo.2012.09.007","title":"A Phase 3, Double-blind, Randomised, Parallel-group, Placebo-controlled Study of Oral Weekly Alendronate for the Prevention of Androgen Deprivation Bone Loss in Nonmetastatic Prostate Cancer: The Cancer and Osteoporosis Research with Alendronate and Leuprolide (CORAL) Study","year":2012,"lang":"en","type":"article","venue":"European Urology","topic":"Bone health and treatments","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre; Sunnybrook Health Science Centre; Health Sciences Centre","funders":"","keywords":"Medicine; Prostate cancer; Osteoporosis; Placebo; Androgen deprivation therapy; Cancer; Oncology; Internal medicine; Randomized controlled trial; Urology; Prostate; Gynecology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00407648,0.0002088234,0.0007049186,0.0001873385,0.0001804136,0.00001138529,0.0001055397,0.00003375941,0.000008971951],"category_scores_gemma":[0.00007385694,0.0001121125,0.00004543313,0.0002541211,0.0002408957,0.0001135806,0.00008761008,0.0002578813,9.443879e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004201195,"about_ca_system_score_gemma":0.0001111844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001997667,"about_ca_topic_score_gemma":0.004597249,"domain_scores_codex":[0.9968942,0.001283565,0.0006751451,0.0003689254,0.0003039954,0.0004741603],"domain_scores_gemma":[0.9984441,0.0005527553,0.0003949509,0.0003308833,0.0001543249,0.0001230048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6062294,0.005189895,0.3634767,0.0001454726,0.0008478956,0.00003831557,0.009323133,0.0001041446,0.0001054098,0.00001110459,0.00002003272,0.01450847],"study_design_scores_gemma":[0.8319497,0.01658306,0.1465418,0.00004590493,0.001457584,0.00005209005,0.002583276,0.0004329162,0.00005678672,0.00002256921,0.0001618445,0.0001124364],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9764776,0.004848921,0.00003092908,0.001072173,0.00004770242,0.01745923,0.00002645786,0.000009450581,0.00002750454],"genre_scores_gemma":[0.9956388,0.0008052887,0.00008952356,0.00006910861,0.00002449733,0.00312529,0.00001547475,0.00004146998,0.000190587],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2257203,"threshold_uncertainty_score":0.4571815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08995542459046717,"score_gpt":0.3921568895774073,"score_spread":0.3022014649869401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}