{"id":"W2067574799","doi":"10.1016/j.chom.2013.06.003","title":"Leishmania Evades Host Immunity by Inhibiting Antigen Cross-Presentation through Direct Cleavage of the SNARE VAMP8","year":2013,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":151,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Institut National de la Recherche Scientifique; McGill University Health Centre; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cross-presentation; Cleavage (geology); Antigen; Antigen presentation; Immunity; Leishmania; Host (biology); Virology; Immunology; Microbiology; Cell biology; Immune system; Parasite hosting; Genetics; T cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001544757,0.0002666637,0.0001798978,0.0002072966,0.0001327601,0.000286911,0.0001900687,0.0003104039,0.001514687],"category_scores_gemma":[0.0001577727,0.0001062802,0.0002097115,0.00005980249,0.0001742243,0.0002335886,0.0002662841,0.0005373665,0.0004181678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002582899,"about_ca_system_score_gemma":0.0001378397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002211735,"about_ca_topic_score_gemma":0.0004007962,"domain_scores_codex":[0.9998643,0.00002981232,0.000007171564,0.00001545681,0.00003079585,0.00005250901],"domain_scores_gemma":[0.9999361,0.00001270939,0.00001714403,0.000005881682,0.00001299166,0.00001512107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002180747,0.00003864353,0.0002532634,0.00005320589,0.00001255654,0.00006852471,0.00001202916,0.00006191765,0.9945976,0.0003144651,0.0001559595,0.004213763],"study_design_scores_gemma":[0.00005080749,0.0007568735,0.00420374,0.00001549186,0.00002133693,0.0006431354,0.00004310249,0.001031077,0.9877501,0.0001889568,0.005290762,0.000004716126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898605,0.003713591,0.002729077,0.0003402439,0.00003987393,0.00002716905,0.00009387069,0.0000837824,0.003111956],"genre_scores_gemma":[0.9953307,0.0009784524,0.0009094878,0.00007757788,0.00001660708,0.00001243862,0.0001456478,0.00000992793,0.002519166],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001514687,"threshold_uncertainty_score":0.00506711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02042483357840603,"score_gpt":0.3016788551479462,"score_spread":0.2812540215695402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}