{"id":"W2067579208","doi":"10.1152/ajpheart.01107.2003","title":"Phospholipase C gene expression, protein content, and activities in cardiac hypertrophy and heart failure due to volume overload","year":2004,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Internal medicine; Endocrinology; Volume overload; Ventricle; Phosphatidylinositol; Muscle hypertrophy; Isozyme; Gene expression; Inositol; Heart failure; Biology; Phospholipase C; Medicine; Chemistry; Enzyme; Gene; Signal transduction; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001264319,0.0002001777,0.0002079969,0.0004987973,0.0001063303,0.0001965481,0.00007824612,0.000251853,0.0006195204],"category_scores_gemma":[0.0001718302,0.0001548483,0.0001840587,0.0002729217,0.0002350699,0.0002056818,0.0001148166,0.0003835273,0.0001255097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002234449,"about_ca_system_score_gemma":0.0001611493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005666345,"about_ca_topic_score_gemma":0.0005152586,"domain_scores_codex":[0.9999298,0.0000062027,0.00000468897,0.00002402973,0.00001515186,0.00002013053],"domain_scores_gemma":[0.9998293,0.00002559031,0.00005604314,0.00001289302,0.00001933217,0.00005685934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005865383,0.00002648567,0.002192631,0.00002126881,0.000005650149,0.00005289655,0.00002372639,0.00002639331,0.9954683,0.00001940621,0.00001281995,0.001563841],"study_design_scores_gemma":[0.00009804935,0.001798392,0.423271,0.00001326984,0.0001130133,0.0008800623,0.0002048036,0.001331088,0.5706246,0.0002065679,0.001433167,0.00002611099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980007,0.001086153,0.0004948142,0.000027715,0.000006410156,0.000008091027,0.0001711581,0.00001773283,0.0001870835],"genre_scores_gemma":[0.9948891,0.001401849,0.001088583,0.00003938847,0.00002155145,0.0000635895,0.0005706113,0.00001097088,0.001914258],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006195204,"threshold_uncertainty_score":0.002072513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006260268052857517,"score_gpt":0.2070825449846186,"score_spread":0.2008222769317611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}