{"id":"W2067640792","doi":"10.1007/s10529-006-9193-5","title":"Protein biosensors based on the principle of fluorescence resonance energy transfer for monitoring cellular dynamics","year":2006,"lang":"en","type":"review","venue":"Biotechnology Letters","topic":"Advanced Fluorescence Microscopy Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Förster resonance energy transfer; Biosensor; Fluorescence; Biophysics; Fluorescent protein; Nanotechnology; Green fluorescent protein; Chemistry; Biology; Biochemistry; Materials science; Physics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0002104273,0.0005795785,0.0008156681,0.0002315894,0.0001237895,0.00001309876,0.001056383,0.00133791,0.000001035392],"category_scores_gemma":[0.0001043095,0.0004457164,0.0004766285,0.0003215882,0.0006834295,0.000003165181,0.0001114321,0.000442074,0.000001124839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001289638,"about_ca_system_score_gemma":0.000101976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001118697,"about_ca_topic_score_gemma":0.000004575787,"domain_scores_codex":[0.9977378,0.0001164963,0.000602357,0.0008477066,0.0001711357,0.0005245478],"domain_scores_gemma":[0.9982816,0.00005956939,0.000270321,0.001297483,0.00005809949,0.00003293216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004718284,0.00007106215,0.00000360598,0.001455588,0.00004570384,0.000007388676,9.428379e-7,0.00001116107,0.8789324,0.002599533,0.0002567929,0.1165686],"study_design_scores_gemma":[0.00008780793,0.0001448816,2.581363e-7,0.00149582,0.0000452256,0.000002017888,0.000001024578,0.00006246022,0.5549018,0.000009926154,0.4429903,0.0002584636],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009428579,0.6743104,0.3208901,0.0008014548,0.0001660086,0.002323708,0.0003961306,0.0001600353,0.000009266943],"genre_scores_gemma":[0.001221908,0.9165675,0.07877706,0.000234545,0.0002905318,0.001898605,0.0005668989,0.0002771416,0.0001658005],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.4427335,"threshold_uncertainty_score":0.9999586,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01482757404179953,"score_gpt":0.2763615172912759,"score_spread":0.2615339432494764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}