{"id":"W2067667711","doi":"10.1111/imm.12205","title":"The <scp>T</scp>h<scp>POK</scp> transcription factor differentially affects the development and function of self‐specific <scp>CD</scp>8<sup>+</sup><scp>T</scp> cells and regulatory <scp>CD</scp>4<sup>+</sup><scp>T</scp> cells","year":2013,"lang":"en","type":"article","venue":"Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institutes of Health; Canadian Cancer Society Research Institute; National Science Council","keywords":"Biology; FOXP3; Molecular biology; Cell biology; T cell; Transcription factor; Regulatory T cell; Cytotoxic T cell; IL-2 receptor; Immunology; Immune system; Biochemistry; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","sts","research_integrity"],"category_scores_codex":[0.00263045,0.003910052,0.004186236,0.00180742,0.004033005,0.0009006017,0.003793614,0.005498059,0.0001706667],"category_scores_gemma":[0.002395696,0.003132145,0.001439349,0.001761976,0.005558808,0.001458063,0.001891259,0.005274697,0.003119958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007734339,"about_ca_system_score_gemma":0.001059464,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003874287,"about_ca_topic_score_gemma":0.0001955067,"domain_scores_codex":[0.9794202,0.004845678,0.004248762,0.004317585,0.001017159,0.006150635],"domain_scores_gemma":[0.9710164,0.02028313,0.002846044,0.003946726,0.001264189,0.0006435027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005989191,0.001752832,0.002448014,0.0004572627,0.005012455,0.00006655201,0.02825142,0.0001924612,0.8810898,0.001485773,0.07228231,0.006901233],"study_design_scores_gemma":[0.00710762,0.002061845,0.03865217,0.0002568771,0.0009895818,0.0004403587,0.02903316,0.0001528622,0.4151269,0.0007581149,0.5051375,0.0002830051],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9287257,0.05388069,0.0007139707,0.0002018041,0.006286352,0.004708219,0.0004122146,0.001183592,0.003887439],"genre_scores_gemma":[0.9353849,0.0128157,0.0005069646,0.0005911448,0.000730227,0.001160011,0.0009395204,0.000647522,0.047224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4659629,"threshold_uncertainty_score":0.9976562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009677903616936942,"score_gpt":0.1871098825213772,"score_spread":0.1774319789044402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}