{"id":"W2067682536","doi":"10.1097/eja.0b013e3283382014","title":"Requested retraction of six studies on the PK/PD and tolerability of fospropofol","year":2010,"lang":"en","type":"letter","venue":"European Journal of Anaesthesiology","topic":"Anesthesia and Sedative Agents","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Tolerability; Propofol; Anesthesiology; Pharmacokinetics; Pharmacology; Anesthesia; Adverse effect","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.01577647,0.001489551,0.002274342,0.001885857,0.002125569,0.003771436,0.00311054,0.01732972,0.008634209],"category_scores_gemma":[0.1202879,0.0009475558,0.002979582,0.001174059,0.002246636,0.002262612,0.002277814,0.01440967,0.009974982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003984272,"about_ca_system_score_gemma":0.003362661,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001153236,"about_ca_topic_score_gemma":0.001415251,"domain_scores_codex":[0.9825556,0.004593644,0.004703375,0.0009958318,0.006032866,0.001118641],"domain_scores_gemma":[0.9194342,0.03922094,0.01157285,0.003610861,0.02326701,0.002894152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002736704,0.0000281068,0.0004414849,0.0008620811,0.0001121102,0.002465411,0.0001207301,0.00007155521,0.0006440914,0.001250912,0.9717422,0.02198775],"study_design_scores_gemma":[0.0002011369,0.0001326907,0.001170082,0.0008709973,0.0001514043,0.003799764,0.0001286102,0.0003403394,0.001049587,0.001457304,0.9906471,0.00005091308],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001734519,0.008575759,0.001725576,0.5280222,0.4541469,0.0001727213,0.0004919565,0.0002636264,0.004866799],"genre_scores_gemma":[0.01702937,0.0088924,0.002846746,0.4434936,0.5075554,0.0003724393,0.0004749097,0.0002742059,0.01906082],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.9826702,"threshold_uncertainty_score":0.08343494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07142981868017592,"score_gpt":0.3085278359904046,"score_spread":0.2370980173102286,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}