{"id":"W2067690613","doi":"10.1038/nature07749","title":"A hierarchical model for evolution of 23S ribosomal RNA","year":2009,"lang":"en","type":"article","venue":"Nature","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":233,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Ribosome; Abiogenesis; RNA world hypothesis; RNA; Ribosomal RNA; 5.8S ribosomal RNA; Biology; Simple (philosophy); Evolutionary biology; Computational biology; Genetics; Philosophy; Epistemology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001080463,0.0004085199,0.0006902092,0.001007616,0.001386994,0.001964035,0.002029953,0.001711276,0.00602186],"category_scores_gemma":[0.001963931,0.0005478418,0.001446876,0.0009167333,0.001622424,0.002595103,0.0009616448,0.001116213,0.001533744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002607733,"about_ca_system_score_gemma":0.001317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007995203,"about_ca_topic_score_gemma":0.007157843,"domain_scores_codex":[0.9994956,0.000158262,0.00002173204,0.0001251582,0.0001015119,0.00009777827],"domain_scores_gemma":[0.9992151,0.0003675941,0.00006652583,0.0001244997,0.0001204564,0.0001058884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00006086157,0.00004179474,0.002027947,0.0001188958,0.00006462773,0.0003088867,0.0005009766,0.1539382,0.008215052,0.8133997,0.001959849,0.01936324],"study_design_scores_gemma":[0.00003660369,0.00004324525,0.001430543,0.00001998459,0.00003499009,0.0001742323,0.0000798075,0.286972,0.0006025034,0.7056502,0.004917257,0.00003866864],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2477394,0.002214741,0.6562751,0.004190096,0.0001613235,0.0001165202,0.0007287251,0.001284389,0.08728974],"genre_scores_gemma":[0.9002911,0.0009609562,0.08184283,0.0004200189,0.00007752981,0.0001842544,0.0003919188,0.0001725178,0.01565885],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.007995203,"threshold_uncertainty_score":0.02014512,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007232802767355916,"score_gpt":0.252992030366577,"score_spread":0.2457592275992211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}