{"id":"W2067751168","doi":"10.1016/j.trivac.2013.12.001","title":"HIV-1 Gag-specific exosome-targeted T cell-based vaccine stimulates effector CTL responses leading to therapeutic and long-term immunity against Gag/HLA-A2-expressing B16 melanoma in transgenic HLA-A2 mice","year":2014,"lang":"en","type":"article","venue":"Trials in Vaccinology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"CTL*; Virology; Cytotoxic T cell; CD8; Biology; Immunology; Group-specific antigen; Epitope; Cellular immunity; Immunity; Immune system; Antigen; Virus; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001515054,0.0005864797,0.0003232802,0.0001960033,0.00009205619,0.000231777,0.0001503749,0.0003416475,0.0009170639],"category_scores_gemma":[0.00009462102,0.0001623974,0.0002877073,0.00008551302,0.0001939197,0.0002804978,0.0001549053,0.001367074,0.0002736669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001467776,"about_ca_system_score_gemma":0.0001671198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001658119,"about_ca_topic_score_gemma":0.0002488863,"domain_scores_codex":[0.9998251,0.00002570789,0.00002135329,0.00004181498,0.00003170824,0.00005442272],"domain_scores_gemma":[0.9998837,0.00001845748,0.00002954624,0.00001453881,0.000008231915,0.00004553786],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002479885,0.000198132,0.000103778,0.00003389506,0.000005167878,0.00002549134,0.00001508301,0.00007647977,0.9983333,0.00004988027,0.000033559,0.0008773149],"study_design_scores_gemma":[0.0001005801,0.002382711,0.002136917,0.000009991298,0.00002922625,0.0002048288,0.00002491761,0.001407487,0.9925982,0.00005386547,0.001046467,0.000004869253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973131,0.0003907197,0.001167299,0.00007405698,0.00003449877,0.0000412969,0.0002052212,0.00006767394,0.0007061137],"genre_scores_gemma":[0.9951738,0.0003832495,0.001476957,0.00007121598,0.00002003906,0.00005489653,0.0003992023,0.00001833356,0.002402303],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009170639,"threshold_uncertainty_score":0.003067911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0390011234271553,"score_gpt":0.3002517028796073,"score_spread":0.2612505794524521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}