{"id":"W2067875575","doi":"10.1074/jbc.m100188200","title":"Functional Roles for the Cytoplasmic Domain of the Type III Transforming Growth Factor β Receptor in Regulating Transforming Growth Factor β Signaling","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"National Cancer Institute","keywords":"Transforming growth factor; Cell biology; Cytoplasm; Domain (mathematical analysis); Signal transduction; Growth factor; Transforming growth factor, beta 3; Factor (programming language); Receptor; TGF alpha; Biology; Genetics; Computer science; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001208598,0.0002618975,0.0001444471,0.0001368567,0.0001445574,0.0005189207,0.0002997732,0.0003302727,0.001107418],"category_scores_gemma":[0.0001400907,0.0001034361,0.0004155031,0.00008197066,0.0002648641,0.0002591214,0.0002168368,0.0004826999,0.0005684686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003880991,"about_ca_system_score_gemma":0.0002508412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007540944,"about_ca_topic_score_gemma":0.0005963717,"domain_scores_codex":[0.9998932,0.00001829005,0.000007589043,0.00001913326,0.00002573486,0.00003594942],"domain_scores_gemma":[0.9998866,0.00001565352,0.00002888546,0.00001274921,0.00001953806,0.0000365832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001086441,0.00001100973,0.0005003518,0.00003550427,0.000005757338,0.0002223565,0.00001193473,0.00004537991,0.9973977,0.0004841542,0.00004992243,0.001127454],"study_design_scores_gemma":[0.0001242059,0.0003938167,0.03744875,0.00006505121,0.0001047313,0.007088234,0.0002565634,0.003403102,0.9342806,0.0006640978,0.01613667,0.00003414307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9749929,0.01123266,0.008840709,0.0003653544,0.0001110031,0.00002566556,0.0002231032,0.00007632004,0.004132245],"genre_scores_gemma":[0.9925491,0.002736238,0.002222281,0.0001604512,0.00003747293,0.00001499108,0.0003376034,0.00002252832,0.001919232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001107418,"threshold_uncertainty_score":0.003704727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02241377411456059,"score_gpt":0.2444626522289721,"score_spread":0.2220488781144115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}