{"id":"W2067925490","doi":"10.1038/srep08543","title":"Reliable Genotypic Tropism Tests for the Major HIV-1 Subtypes","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"AIDS Vancouver","funders":"National Institute of Mental Health; Medical Research Council; National Institutes of Health; University of Melbourne; Burnet Institute; National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council; Delaney AIDS Research Enterprise","keywords":"Maraviroc; Tropism; CCR5 receptor antagonist; Virology; Tissue tropism; Human immunodeficiency virus (HIV); Genotype; Biology; Lentivirus; Medicine; Virus; Immunology; Viral disease; Genetics; Gene; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001605218,0.0006921422,0.0003868168,0.000851551,0.0003228828,0.0006005667,0.0004960814,0.0006707934,0.002213736],"category_scores_gemma":[0.003478851,0.0002882495,0.0003208995,0.0004348927,0.0004801002,0.0004742605,0.0007162737,0.000804181,0.001276037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002200222,"about_ca_system_score_gemma":0.0003413331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006081892,"about_ca_topic_score_gemma":0.001258361,"domain_scores_codex":[0.9974643,0.001077915,0.0001738172,0.0003347744,0.0007640362,0.0001851766],"domain_scores_gemma":[0.9982554,0.0006300163,0.0003820027,0.0002028383,0.0004205638,0.0001091635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005878403,0.0001780124,0.04377874,0.0002450389,0.00005404401,0.0001480969,0.0002425892,0.001319075,0.8811785,0.001967805,0.002455914,0.06784435],"study_design_scores_gemma":[0.0000751925,0.001734416,0.09597349,0.0001280561,0.0001113302,0.002270482,0.0002596229,0.00843503,0.8660269,0.001722726,0.02313526,0.0001275529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7937039,0.004650855,0.1535279,0.0008336491,0.0002917322,0.001915876,0.01136191,0.001969901,0.03174435],"genre_scores_gemma":[0.8851537,0.002076613,0.1008475,0.0007240376,0.00007289585,0.0007565727,0.005142997,0.0001541758,0.00507163],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002213736,"threshold_uncertainty_score":0.008489251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0315756523656379,"score_gpt":0.2821748682312622,"score_spread":0.2505992158656243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}