{"id":"W2067982008","doi":"10.1074/jbc.m002945200","title":"Expression of the α5 Integrin Subunit Gene Promoter Is Positively Regulated by the Extracellular Matrix Component Fibronectin through the Transcription Factor Sp1 in Corneal Epithelial Cells in Vitro","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"","keywords":"Fibronectin; Molecular biology; Biology; Integrin; Transcription factor; Promoter; Signal transduction; Cell biology; Extracellular matrix; Gene expression; Gene; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003340132,0.0002863977,0.0002625941,0.0002652832,0.0001819517,0.0004112226,0.0002083512,0.0001652807,0.000987061],"category_scores_gemma":[0.0002567047,0.0002285182,0.0003588439,0.0001918165,0.0002303325,0.0001463053,0.000313005,0.0005406234,0.0005656209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003717464,"about_ca_system_score_gemma":0.0002358426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001527272,"about_ca_topic_score_gemma":0.001759901,"domain_scores_codex":[0.9996259,0.00008411882,0.00004444052,0.00006218644,0.0001108718,0.00007242925],"domain_scores_gemma":[0.9998109,0.00005614659,0.00003223923,0.00002970088,0.00003622386,0.00003490313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004448725,0.00001422804,0.0001509595,0.00001777198,0.000001951322,0.0000204012,0.00002540872,0.00002667844,0.998973,0.00005489707,0.00002321732,0.0006469481],"study_design_scores_gemma":[0.00001498518,0.000202449,0.00611496,0.00001464161,0.00001610894,0.0002241493,0.00008112711,0.002785538,0.9882124,0.00007508428,0.002252497,0.000006045278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836137,0.002766875,0.01089342,0.0001374046,0.0000521363,0.00004059868,0.0005373819,0.00005786757,0.001900633],"genre_scores_gemma":[0.9855831,0.001332129,0.007441064,0.00006732934,0.00002914861,0.00004710972,0.001546637,0.00003262448,0.003920933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001527272,"threshold_uncertainty_score":0.003302038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02796298473013045,"score_gpt":0.2785061464400968,"score_spread":0.2505431617099664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}