{"id":"W2067992137","doi":"10.1016/j.chembiol.2007.07.011","title":"Deconvolution of the Cellular Oxidative Stress Response with Organelle-Specific Peptide Conjugates","year":2007,"lang":"en","type":"article","venue":"Chemistry & Biology","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Camille and Henry Dreyfus Foundation; National Science Foundation","keywords":"Oxidative stress; Organelle; Mitochondrion; Reactive oxygen species; Biology; Oxidative phosphorylation; Cell biology; Cell; Subcellular localization; Function (biology); Cytoplasm; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004113679,0.0005077803,0.0003751318,0.000273033,0.0002545359,0.0004149363,0.0003250135,0.0004944147,0.001513765],"category_scores_gemma":[0.0003501708,0.0002365128,0.0003511774,0.0003480001,0.000270906,0.0004646385,0.0003402705,0.001041268,0.000356023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004197313,"about_ca_system_score_gemma":0.000405396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005471498,"about_ca_topic_score_gemma":0.0006819899,"domain_scores_codex":[0.9998562,0.00002235427,0.000004639387,0.00003886916,0.00003667518,0.00004112365],"domain_scores_gemma":[0.9997928,0.00005839062,0.00004717077,0.000029353,0.00003902491,0.0000333148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001832822,0.00001173814,0.000127522,0.00003584319,0.000007012475,0.00002688877,0.00001709084,0.000226633,0.9977109,0.0002148105,0.00003005016,0.001408149],"study_design_scores_gemma":[0.000006019962,0.0000643977,0.001085952,0.000001868356,0.000007403874,0.00003598101,0.00001078862,0.002200735,0.9960444,0.00008002127,0.0004577628,0.000004652612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9361283,0.0006617483,0.06074268,0.0001104399,0.00004247787,0.00004232514,0.0002300755,0.0002096766,0.001832301],"genre_scores_gemma":[0.9689698,0.001061301,0.02486949,0.0001176638,0.00001998606,0.0001088717,0.0004743295,0.0001077366,0.004270751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001513765,"threshold_uncertainty_score":0.00506407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006577569771727098,"score_gpt":0.2276130563520446,"score_spread":0.2210354865803175,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}