{"id":"W2068012965","doi":"10.1002/mc.20278","title":"Adenovirus E1A requires c‐Ras for full neoplastic transformation or suppression of differentiation of murine preadipocytes","year":2007,"lang":"en","type":"article","venue":"Molecular Carcinogenesis","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Biology; Gene knockdown; Downregulation and upregulation; Cellular differentiation; Cell biology; Neoplastic transformation; E2F; Cancer research; Transfection; Apoptosis; Molecular biology; Gene; Cell cycle; Carcinogenesis; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003898564,0.0001993295,0.000264275,0.0001853402,0.00005867294,0.000008681565,0.0002364329,0.0001816814,0.00003358018],"category_scores_gemma":[0.0001351553,0.000173915,0.0002061818,0.0001931745,0.0000950593,0.000008995718,0.00005074869,0.00004817466,0.000001167096],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002422651,"about_ca_system_score_gemma":0.0001076228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002855113,"about_ca_topic_score_gemma":0.0001692569,"domain_scores_codex":[0.9984264,0.00009044667,0.0005015709,0.0003066912,0.0003422709,0.0003325533],"domain_scores_gemma":[0.9989629,0.0000642383,0.0001908225,0.0004079413,0.0002823737,0.0000917528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01046312,0.0001270731,0.0008858583,0.000283977,0.0001299158,0.000003810241,0.00011645,0.000349288,0.982119,0.00004285183,0.00003679379,0.005441896],"study_design_scores_gemma":[0.001440043,0.003412189,0.00557122,0.00003753483,0.00009246326,0.000008005446,0.00005429616,0.0003037124,0.9887289,0.00004334978,0.0001307641,0.0001775258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9177687,0.001195486,0.08017048,0.00003581712,0.00007266743,0.0005936351,0.00009585824,0.00001045428,0.00005685954],"genre_scores_gemma":[0.9984451,0.0001126583,0.0008713409,0.0000304986,0.00006310274,0.000051312,0.0003219429,0.00004453548,0.00005953205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08067634,"threshold_uncertainty_score":0.7092046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02005550608009565,"score_gpt":0.2943295032050507,"score_spread":0.2742739971249551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}