{"id":"W2068013953","doi":"10.1007/s00775-011-0782-y","title":"Relationship between the GTPase, metal-binding, and dimerization activities of E. coli HypB","year":2011,"lang":"en","type":"article","venue":"JBIC Journal of Biological Inorganic Chemistry","topic":"Metalloenzymes and iron-sulfur proteins","field":"Energy","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Mutant; GTPase; Escherichia coli; Biochemistry; Stereochemistry; Metal; Hydrogenase; Small GTPase; Enzyme; GTPase-activating protein; Signal transduction; Gene; G protein; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004238085,0.0001338565,0.000317638,0.00002553933,0.00009194119,0.00001407686,0.0002410679,0.0001946115,0.000794996],"category_scores_gemma":[0.0004844457,0.00007691714,0.000112293,0.0001522995,0.0002435229,0.0001020776,0.00008294344,0.0003377748,0.000003351338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002618039,"about_ca_system_score_gemma":0.00004073869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002568638,"about_ca_topic_score_gemma":0.000001173152,"domain_scores_codex":[0.9989524,0.00009827835,0.0005138555,0.0001226704,0.0001586832,0.0001540999],"domain_scores_gemma":[0.998803,0.0002872146,0.0006024526,0.0001623517,0.00006219593,0.00008283462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007248224,0.0001076227,0.123763,0.00005585426,0.0001640248,0.000006131666,0.0004151797,0.00000233895,0.8716488,0.002647709,0.0001030361,0.001013814],"study_design_scores_gemma":[0.0004061797,0.0002101426,0.1850721,0.00003267092,0.0001226251,0.0000692648,0.0005351472,0.000003412901,0.8082346,0.004180338,0.0009857281,0.0001477514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959989,0.0006123881,0.0001936154,0.00009124709,0.00005844052,0.00005517863,0.000008463002,0.00001022849,0.002971562],"genre_scores_gemma":[0.9990198,0.0001077328,0.0002660955,0.00002465363,0.0002016102,0.000001913204,0.00000827754,0.000009822799,0.000360117],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06341413,"threshold_uncertainty_score":0.8704649,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06761828961940473,"score_gpt":0.2498919664213068,"score_spread":0.182273676801902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}