{"id":"W2068051488","doi":"10.1371/journal.pone.0055623","title":"Ezrin Is Required for the Functional Regulation of the Epithelial Sodium Proton Exchanger, NHE3","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children; McGill University; University of Alberta","funders":"Canadian Institutes of Health Research; National Institute of Diabetes and Digestive and Kidney Diseases; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale","keywords":"Ezrin; Moesin; Radixin; Sodium–hydrogen antiporter; Cell biology; Small interfering RNA; Chemistry; Cytoskeleton; Apical membrane; Gene knockdown; Actin cytoskeleton; Transfection; Biology; Molecular biology; Sodium; Biochemistry; Cell; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009417606,0.00007243981,0.00007252701,0.00001256758,0.0000999484,0.000008560958,0.0001008764,0.00008814035,0.0001357829],"category_scores_gemma":[0.00001913587,0.00004452489,0.00008342513,0.00004772916,0.00005896172,0.000005339995,0.00001940193,0.00003145241,0.000007037388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006184231,"about_ca_system_score_gemma":0.00002516121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001945936,"about_ca_topic_score_gemma":0.000008226926,"domain_scores_codex":[0.999426,0.00001614116,0.0001438536,0.0001361988,0.0001729672,0.0001048414],"domain_scores_gemma":[0.9994643,0.00001051636,0.00009116222,0.0002347864,0.0001820766,0.00001710125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001009785,0.0001268719,0.001084934,0.00005990987,0.00007373932,6.806119e-9,0.00006680272,0.00001468103,0.99656,0.00007214332,0.001107923,0.00073195],"study_design_scores_gemma":[0.0003802392,0.00008807758,0.05782585,0.00002196647,0.00004917353,2.856962e-7,0.00002286987,0.0008264236,0.9378235,0.0006295553,0.002270535,0.00006151027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940897,0.0001259128,0.001831516,0.002190272,0.0001125498,0.001492035,0.00002738166,0.000006796399,0.000123903],"genre_scores_gemma":[0.9941065,0.00003018983,0.000173144,0.0001542624,0.0005057156,0.0005065905,0.0001024711,0.00001238818,0.00440869],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05873654,"threshold_uncertainty_score":0.1815672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03821576371570984,"score_gpt":0.2123724293994697,"score_spread":0.1741566656837598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}