{"id":"W2068051488","doi":"10.1371/journal.pone.0055623","title":"Ezrin Is Required for the Functional Regulation of the Epithelial Sodium Proton Exchanger, NHE3","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children; McGill University; University of Alberta","funders":"Canadian Institutes of Health Research; National Institute of Diabetes and Digestive and Kidney Diseases; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale","keywords":"Ezrin; Moesin; Radixin; Sodium–hydrogen antiporter; Cell biology; Small interfering RNA; Chemistry; Cytoskeleton; Apical membrane; Gene knockdown; Actin cytoskeleton; Transfection; Biology; Molecular biology; Sodium; Biochemistry; Cell; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001240864,0.0002542264,0.000275946,0.0001472709,0.0002292882,0.0003766697,0.0001916481,0.0003354112,0.001429882],"category_scores_gemma":[0.0002110039,0.000170141,0.0002475128,0.0001077485,0.0001962401,0.0002321725,0.0003519036,0.0004434295,0.0008022197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003436248,"about_ca_system_score_gemma":0.0001451433,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005713391,"about_ca_topic_score_gemma":0.0006300723,"domain_scores_codex":[0.9998234,0.00002242922,0.00002384324,0.00004251165,0.00004930479,0.00003855493],"domain_scores_gemma":[0.9998227,0.00002375047,0.00006052547,0.00001820097,0.00002184803,0.00005307142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001127704,0.000007108235,0.0003213716,0.00002431325,0.000004705229,0.000132297,0.00001129476,0.00002646077,0.998541,0.00009347399,0.00005045921,0.0006746678],"study_design_scores_gemma":[0.00002444831,0.00008540456,0.03844019,0.000008474126,0.00003407103,0.000929626,0.00006497106,0.00137041,0.9538105,0.00009111413,0.005133383,0.000007369979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994114,0.001540884,0.002568911,0.0001662907,0.00003514918,0.00001086997,0.000418997,0.00008341949,0.001061481],"genre_scores_gemma":[0.9962238,0.0004063311,0.0008232048,0.00004693654,0.000009575387,0.00001201289,0.0004715419,0.00002841464,0.001978181],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001429882,"threshold_uncertainty_score":0.004783452,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03821576371570984,"score_gpt":0.2123724293994697,"score_spread":0.1741566656837598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}