{"id":"W2068089617","doi":"10.1016/j.jaad.2013.12.036","title":"Interleukin 17A: Toward a new understanding of psoriasis pathogenesis","year":2014,"lang":"en","type":"review","venue":"Journal of the American Academy of Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":332,"is_retracted":false,"has_abstract":false,"ca_institutions":"Novartis (Canada); Dermatrials Research; Centre de Recherche Dermatologique du Québec Métropolitain; Lynde Centre for Dermatology","funders":"","keywords":"Psoriasis; Medicine; Immunology; Pathogenesis; Cytokine; Proinflammatory cytokine; Immune system; Inflammation; Chemokine; Interleukin 17","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008574626,0.0007798081,0.00139637,0.001505043,0.0002810701,0.001393503,0.0008864343,0.001389998,0.001991858],"category_scores_gemma":[0.0008662554,0.000261272,0.0003925966,0.001527813,0.0007387443,0.00173285,0.0009094281,0.003113639,0.00127349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007303934,"about_ca_system_score_gemma":0.001740113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009053595,"about_ca_topic_score_gemma":0.001567628,"domain_scores_codex":[0.9997708,0.00004086279,0.00003184689,0.00003385251,0.00009648714,0.00002609127],"domain_scores_gemma":[0.9995089,0.0002023531,0.00007218716,0.00001534219,0.0001431303,0.00005817685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001230519,0.00008103219,0.0003443065,0.00730462,0.00007596468,0.0001864324,0.00005577468,0.0002581564,0.002080234,0.005783543,0.04511777,0.9385891],"study_design_scores_gemma":[0.00003436869,0.00007347322,0.0007498959,0.002074657,0.0001015639,0.001083689,0.00008248496,0.0001144912,0.0004699244,0.004031312,0.9911621,0.00002199957],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006375177,0.9984053,0.0001380424,0.0007000868,0.0003435476,0.000002230175,0.000008197017,0.000005221559,0.000333655],"genre_scores_gemma":[0.0006912444,0.9976145,0.0002087456,0.0004487182,0.0006451795,0.000004524476,0.00001523004,8.861151e-7,0.0003709428],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001991858,"threshold_uncertainty_score":0.006663442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07583151560383232,"score_gpt":0.3313353460327577,"score_spread":0.2555038304289254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}