{"id":"W2068137735","doi":"10.1006/jmbi.2000.3805","title":"The 1.7 Å crystal structure of BPI: a study of how two dissimilar amino acid sequences can adopt the same fold 1 1Edited by D. Rees","year":2000,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; U.S. Public Health Service; Ryerson University; University of Missouri","keywords":"Structural similarity; Crystal structure; Crystallography; Protein secondary structure; Residue (chemistry); Protein structure; Fold (higher-order function); Structural alignment; Chemistry; Sequence alignment; Peptide sequence; Computer science; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002839803,0.0006932849,0.001057444,0.0003679102,0.001172526,0.001283879,0.001664244,0.001112965,0.003867884],"category_scores_gemma":[0.0007576297,0.0006062542,0.0002846512,0.000812194,0.0005055038,0.0009239827,0.0004834397,0.004026649,0.001106958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001027692,"about_ca_system_score_gemma":0.0009928425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003375443,"about_ca_topic_score_gemma":0.005003616,"domain_scores_codex":[0.999821,0.00001873344,0.000005359978,0.00002955008,0.00009742293,0.00002798626],"domain_scores_gemma":[0.9997988,0.00005982632,0.00003050802,0.00001037896,0.00003412131,0.00006641586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00212717,0.00126013,0.004999673,0.002133823,0.0002272817,0.004919166,0.001454009,0.01658668,0.7591887,0.03371176,0.09712698,0.07626471],"study_design_scores_gemma":[0.002138482,0.00287722,0.02704414,0.0007058743,0.0006526142,0.008754729,0.002713774,0.1743607,0.4420886,0.01958952,0.318518,0.00055625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9213148,0.019946,0.01372849,0.006785377,0.001891128,0.0001444381,0.003900399,0.001693527,0.03059579],"genre_scores_gemma":[0.9139093,0.01605193,0.0414554,0.00167125,0.0003798046,0.0001561521,0.01173135,0.0004055554,0.0142392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003867884,"threshold_uncertainty_score":0.01293939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005360553035290302,"score_gpt":0.2406912842168666,"score_spread":0.2353307311815763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}