{"id":"W2068189812","doi":"10.1210/en.2015-1020","title":"Periostin Conditions the Matrix to Generate a Niche for Islet Regeneration","year":2015,"lang":"en","type":"letter","venue":"Endocrinology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Islet; Regeneration (biology); Internal medicine; Periostin; Endocrinology; Niche; Matrix (chemical analysis); Cell biology; Biology; Medicine; Chemistry; Diabetes mellitus; Extracellular matrix; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005407275,0.0006562021,0.0002705589,0.0007955081,0.000493728,0.0006791115,0.0004277715,0.0008614837,0.01067298],"category_scores_gemma":[0.0002223735,0.0003742224,0.0003835016,0.0002685481,0.0006329173,0.0005871551,0.0007885845,0.001922839,0.003083252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004677628,"about_ca_system_score_gemma":0.0005880236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004356088,"about_ca_topic_score_gemma":0.001956096,"domain_scores_codex":[0.9996056,0.00004447463,0.00002185569,0.00008203402,0.0001594462,0.00008667181],"domain_scores_gemma":[0.9997123,0.00005169357,0.0000876393,0.00004322901,0.00002844086,0.00007667252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007216357,0.00004853564,0.00009623491,0.00008083223,0.000004718809,0.0001426074,0.00002918214,0.0001354707,0.9925871,0.00185918,0.0006370991,0.004306778],"study_design_scores_gemma":[0.00007631408,0.0004784861,0.002533676,0.00008077318,0.00002452639,0.001635039,0.00005575223,0.002538538,0.8983358,0.001197553,0.09301943,0.00002401304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6083398,0.01463849,0.2771421,0.003744553,0.002883942,0.001199489,0.002905224,0.004519336,0.08462699],"genre_scores_gemma":[0.7975652,0.003566896,0.1403958,0.00108896,0.000365056,0.001090151,0.002315434,0.001004537,0.05260794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01067298,"threshold_uncertainty_score":0.03570467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0475337819442683,"score_gpt":0.331133307598287,"score_spread":0.2835995256540187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}