{"id":"W2068313649","doi":"10.1016/j.yexcr.2013.10.016","title":"Fatty acid synthase plays a role in cancer metabolism beyond providing fatty acids for phospholipid synthesis or sustaining elevations in glycolytic activity","year":2013,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Glycolysis; Cancer cell; Biochemistry; Lipogenesis; Phospholipid; Fatty acid synthesis; Fatty acid; Metabolism; Lipid metabolism; Warburg effect; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003587488,0.0004473363,0.0002163544,0.0003681663,0.0004425413,0.0009600665,0.0002440412,0.0005187414,0.001755627],"category_scores_gemma":[0.0002486809,0.000146499,0.0001969447,0.0003877335,0.0009695094,0.0009507631,0.0004515946,0.0007260228,0.0003772324],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006975346,"about_ca_system_score_gemma":0.0007433649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00115542,"about_ca_topic_score_gemma":0.001414346,"domain_scores_codex":[0.9999121,0.00002128866,0.000006372114,0.00002154092,0.00001662659,0.00002212303],"domain_scores_gemma":[0.9998374,0.00003122305,0.00002608092,0.00001966207,0.00002731068,0.00005827723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001676966,0.00007328565,0.005143145,0.0002374258,0.00003104969,0.0004306013,0.00009231878,0.000337324,0.9544681,0.01933195,0.0005391368,0.01763878],"study_design_scores_gemma":[0.0000738327,0.0005834438,0.01337725,0.00005885479,0.00006547206,0.001338461,0.0004124175,0.001155287,0.949964,0.008031929,0.02490882,0.00003019571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9052807,0.05636182,0.01396339,0.009017701,0.0005797654,0.00004722367,0.001012531,0.0002598204,0.01347706],"genre_scores_gemma":[0.9812201,0.01082005,0.002586731,0.0002096753,0.00006074924,0.00001417312,0.000280708,0.0000139502,0.004793865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001755627,"threshold_uncertainty_score":0.005873144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0412701995431823,"score_gpt":0.3591253201468844,"score_spread":0.3178551206037021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}