{"id":"W2068389722","doi":"10.1074/jbc.m301590200","title":"Identification of Ets-1 as an Important Transcriptional Activator of CTP: Phosphocholine Cytidylyltransferase α in COS-7 Cells and Co-activation with Transcriptional Enhancer Factor-4","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; University of Alberta; Canadian Institutes of Health Research","funders":"Canadian Institutes of Health Research; Naito Foundation","keywords":"Phosphocholine; Molecular biology; Enhancer; Transcription factor; Transfection; Transcription (linguistics); Activator (genetics); Luciferase; Reporter gene; Promoter; Biology; Transcriptional regulation; Gene expression; Chemistry; Gene; Phosphatidylcholine; Biochemistry; Phospholipid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003568245,0.0001383036,0.0002426495,0.00003216098,0.00002551175,0.000008968897,0.00008543622,0.0002015437,0.0001380138],"category_scores_gemma":[0.00006650816,0.0001056822,0.00008890301,0.00008877146,0.0001473778,0.00002281563,0.000003155764,0.000151131,1.066102e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002564914,"about_ca_system_score_gemma":0.0001593414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003571133,"about_ca_topic_score_gemma":0.000001019078,"domain_scores_codex":[0.9987383,0.00006404175,0.0006658932,0.0001951537,0.0002125512,0.0001240205],"domain_scores_gemma":[0.9991668,0.00001784781,0.0004071467,0.0001025258,0.0002067891,0.00009882608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009704207,0.0002809485,0.002455696,0.00005929298,0.00003462786,0.000003145021,0.0000531229,0.0000888775,0.9957789,0.000110416,0.000002395795,0.0001621485],"study_design_scores_gemma":[0.001270191,0.0003903411,0.008300713,0.00004709895,0.00001268368,0.00005056917,0.0001162573,0.00001501169,0.9891173,0.0001559053,0.0004040728,0.0001199139],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956264,0.0005112985,0.00357787,0.00003472852,0.0000202236,0.0001056581,0.00007457093,0.000002111377,0.00004717371],"genre_scores_gemma":[0.9990624,0.0003060565,0.0004523625,0.00003093564,0.00004995754,0.000004729986,0.00006896254,0.000008010527,0.00001663868],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006661666,"threshold_uncertainty_score":0.4309595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0152945785593587,"score_gpt":0.2615711324985172,"score_spread":0.2462765539391585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}