{"id":"W2068417296","doi":"10.1042/bj20020768","title":"A re-evaluation of the role of histidine-426 within Pseudomonas aeruginosa exotoxin A","year":2002,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"Pseudomonas aeruginosa; Pseudomonas exotoxin; Histidine; Microbiology; Exotoxin; Biology; Chemistry; Bacteria; Biochemistry; Genetics; Amino acid; Toxin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007570975,0.0001322642,0.0002498797,0.00006572666,0.0001125682,0.000007974828,0.0003845154,0.0002336569,0.001807731],"category_scores_gemma":[0.000377413,0.00009209207,0.0002055113,0.0001512437,0.000213926,0.00005030012,0.00008888871,0.0004391687,0.00003783907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006378363,"about_ca_system_score_gemma":0.00007057851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001397626,"about_ca_topic_score_gemma":0.000002190539,"domain_scores_codex":[0.9986404,0.0002760146,0.0005382465,0.0001506319,0.0001778924,0.0002167752],"domain_scores_gemma":[0.998907,0.00005494024,0.0004721896,0.0003001003,0.0002387461,0.00002701338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005154615,0.0001799164,0.0002665757,0.000005775695,0.00008274109,5.162915e-7,0.0004298846,0.0000048536,0.9923191,0.0003348367,0.002338514,0.003985708],"study_design_scores_gemma":[0.001208545,0.0001073893,0.0006170014,0.00008735004,0.0001057493,0.0001701921,0.0004221714,0.0001125202,0.9937062,0.001662282,0.001697324,0.0001032973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880649,0.009700987,0.00004689446,0.0002242607,0.0005669904,0.0001857452,0.0000176709,0.00001005659,0.001182489],"genre_scores_gemma":[0.99922,0.00007442416,0.0003214239,0.0000509993,0.0000525145,0.000006932133,0.000003787015,0.00001117699,0.0002588161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01115502,"threshold_uncertainty_score":0.9991047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02315263413320439,"score_gpt":0.2365892120455639,"score_spread":0.2134365779123595,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}