{"id":"W2068516450","doi":"10.1002/chin.200051209","title":"ChemInform Abstract: Syntheses of 4‐[1‐(2‐Deoxy‐β‐D‐ribofuranosyl)] Derivatives of 2‐Substituted‐5‐fluoroaniline: “Cytosine Replacement” Analogues of Deoxycytidine for Evaluation as Anticancer and antihuman Immunodeficiency Virus (anti‐HIV) Agents.","year":2000,"lang":"en","type":"article","venue":"ChemInform","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Human immunodeficiency virus (HIV); Deoxycytidine; Cytosine; Chemistry; Virology; Combinatorial chemistry; Stereochemistry; Medicine; DNA; Biochemistry; Chemotherapy; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002338797,0.0009442457,0.0003801468,0.0004676846,0.0003179717,0.0002845307,0.0005836544,0.0004211258,0.009021814],"category_scores_gemma":[0.0002119306,0.0002664235,0.0003257099,0.0005814451,0.0001971495,0.0005023559,0.0002216536,0.0005496787,0.003690685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004747918,"about_ca_system_score_gemma":0.0009922161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001051349,"about_ca_topic_score_gemma":0.00179672,"domain_scores_codex":[0.9998606,0.00002692882,0.00001068159,0.00002785647,0.00003477038,0.00003898906],"domain_scores_gemma":[0.9999291,0.000007584395,0.00001803889,0.000007974815,0.00001522603,0.00002214525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001876554,0.0005159628,0.0004395445,0.002638162,0.0001393093,0.001205643,0.0003507132,0.004268591,0.8222897,0.005055068,0.0196969,0.1415239],"study_design_scores_gemma":[0.0004676709,0.002448821,0.001852254,0.000101219,0.0001229205,0.001094569,0.00004252569,0.000905262,0.8830517,0.0005366887,0.1093061,0.0000701508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5808995,0.07526589,0.07991128,0.001676969,0.002817936,0.002495306,0.02612715,0.002631063,0.2281749],"genre_scores_gemma":[0.8638861,0.03579758,0.03433089,0.0007970727,0.0003614547,0.0004350212,0.01329123,0.0003057337,0.05079481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009021814,"threshold_uncertainty_score":0.03018099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02922417080976206,"score_gpt":0.307520297315714,"score_spread":0.2782961265059519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}