{"id":"W2068525838","doi":"10.1158/1538-7445.am2014-lb-202","title":"Abstract LB-202: The rare, highly malignant small cell carcinoma of the ovary displays common inactivating germline and somatic mutations in the tumor suppressor SMARCA4","year":2014,"lang":"en","type":"article","venue":"Cancer Research","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of British Columbia","funders":"","keywords":"SMARCA4; Germline; Biology; Germline mutation; Ovarian cancer; Cancer research; Ovarian carcinoma; Ovary; Somatic cell; Pathology; Cancer; Mutation; Internal medicine; Medicine; Endocrinology; Chromatin remodeling; Genetics; Epigenetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001163404,0.0002974235,0.0002441806,0.0009277831,0.0003105841,0.0003183885,0.0001809011,0.0003581905,0.001630497],"category_scores_gemma":[0.0004680567,0.0001228929,0.0001695216,0.0004610548,0.0003475515,0.0001229719,0.0002311751,0.0001986985,0.0004909592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002831865,"about_ca_system_score_gemma":0.0001959856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001695463,"about_ca_topic_score_gemma":0.001984112,"domain_scores_codex":[0.9998389,0.00001321426,0.00001730398,0.00003890438,0.00004112395,0.00005046248],"domain_scores_gemma":[0.9997523,0.0000627352,0.00006818946,0.00002208678,0.00002464048,0.00006996195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007013128,0.0001528068,0.315198,0.000155503,0.00005809174,0.2210562,0.0002919305,0.0002088271,0.4474306,0.0005254627,0.001097369,0.01312389],"study_design_scores_gemma":[0.00005591473,0.0004931727,0.4521708,0.00002059599,0.00006623766,0.4732736,0.0003251083,0.001398636,0.0669383,0.000339556,0.004895065,0.00002289256],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964482,0.0005247545,0.0005626684,0.00006412626,0.00001464852,0.00002790883,0.000314131,0.000045799,0.001997861],"genre_scores_gemma":[0.9991755,0.0000712223,0.0001892238,0.00003107285,0.000008685512,0.000004893532,0.0001712661,0.000006880725,0.0003411914],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001695463,"threshold_uncertainty_score":0.00545454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03393921870807376,"score_gpt":0.3172899061806839,"score_spread":0.2833506874726101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}