{"id":"W2068525838","doi":"10.1158/1538-7445.am2014-lb-202","title":"Abstract LB-202: The rare, highly malignant small cell carcinoma of the ovary displays common inactivating germline and somatic mutations in the tumor suppressor SMARCA4","year":2014,"lang":"en","type":"article","venue":"Cancer Research","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of British Columbia","funders":"","keywords":"SMARCA4; Germline; Biology; Germline mutation; Ovarian cancer; Cancer research; Ovarian carcinoma; Ovary; Somatic cell; Pathology; Cancer; Mutation; Internal medicine; Medicine; Endocrinology; Chromatin remodeling; Genetics; Epigenetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001088232,0.0001159117,0.0001380657,0.00003769624,0.0002646512,0.00004452713,0.0005175887,0.00006087528,0.00001430389],"category_scores_gemma":[0.0001162238,0.00006060669,0.00005928851,0.0001802075,0.0003315218,0.000004837676,0.0002095377,0.000344422,0.000001043702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003521604,"about_ca_system_score_gemma":0.0001775222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002101244,"about_ca_topic_score_gemma":0.0009173405,"domain_scores_codex":[0.9985192,0.0003849289,0.0002611991,0.0002429745,0.0002937603,0.0002978795],"domain_scores_gemma":[0.9988998,0.0003075165,0.0001026357,0.0005536415,0.0000989735,0.00003746174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000720945,0.00008534018,0.01310133,0.0003425953,0.0000146913,0.000003307696,0.001011887,0.0009766428,0.9818706,0.0001377483,0.0007417875,0.001641966],"study_design_scores_gemma":[0.0009441384,0.0001557208,0.1893043,0.0002256596,0.0000230452,0.00001660962,0.002277744,0.004396872,0.8008195,0.0005979678,0.001051929,0.0001864387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961194,0.001282659,0.0000369578,0.001264598,0.00005689438,0.0003975063,0.00004094296,0.0000029481,0.0007980436],"genre_scores_gemma":[0.9992703,0.00006469137,0.00004365272,0.0001590546,0.0001448294,0.0001659512,0.00002019624,0.00001876642,0.0001126135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1810511,"threshold_uncertainty_score":0.3176466,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03393921870807376,"score_gpt":0.3172899061806839,"score_spread":0.2833506874726101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}