{"id":"W2068541511","doi":"10.1016/j.drup.2004.07.002","title":"Leishmaniasis: drugs in the clinic, resistance and new developments","year":2004,"lang":"en","type":"review","venue":"Drug Resistance Updates","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":403,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"Centers for Disease Control and Prevention","keywords":"Miltefosine; Pentamidine; Leishmaniasis; Leishmania; Medicine; Antifungal drugs; Amphotericin B; Drug resistance; Antifungal; Pharmacology; Fluconazole; Intensive care medicine; Immunology; Visceral leishmaniasis; Biology; Dermatology; Internal medicine; Microbiology; Pneumonia; Parasite hosting; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001950837,0.0009378267,0.003031614,0.000509827,0.0003230118,0.000236661,0.001015974,0.0003378083,0.00009861014],"category_scores_gemma":[0.0009193463,0.0006186926,0.000428301,0.001357844,0.0004318048,0.0002306891,0.0003331375,0.001469924,0.0003512252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007002895,"about_ca_system_score_gemma":0.002057282,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006782104,"about_ca_topic_score_gemma":0.001964471,"domain_scores_codex":[0.9942049,0.0005071255,0.001617725,0.001321495,0.001295494,0.001053268],"domain_scores_gemma":[0.996525,0.001110717,0.0005819972,0.001300806,0.0001690364,0.0003123838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005011953,0.0005178897,0.0006767788,0.10354,0.001338356,0.001053048,0.007169589,6.211141e-8,3.272118e-7,0.002662846,0.4472138,0.435326],"study_design_scores_gemma":[0.001182136,0.00001851933,0.001099971,0.04948278,0.0004611702,0.00002808626,0.0007964158,3.027099e-8,0.000001879641,0.0007445295,0.9456463,0.000538216],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000677912,0.9787748,0.000002129958,0.004159588,0.0001428874,0.002378875,0.00004138586,0.0000912042,0.01434137],"genre_scores_gemma":[0.00005792103,0.939746,0.002311092,0.00040273,0.0002403271,0.000410589,0.0001492619,0.0001288394,0.05655322],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.4984324,"threshold_uncertainty_score":0.9996265,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06026731808428146,"score_gpt":0.3660137248391854,"score_spread":0.3057464067549039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}