{"id":"W2068574639","doi":"10.1002/ijc.20043","title":"Synergistic effect of lymphotactin and interferon γ‐inducible protein‐10 transgene expression in T‐cell localization and adoptive T‐cell therapy of tumors","year":2004,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"University of Saskatchewan","keywords":"CD8; Adoptive cell transfer; Cytotoxic T cell; CXCR3; Biology; T cell; Granzyme B; Molecular biology; Transgene; Immunology; Cancer research; Chemokine; In vitro; Antigen; Immune system; Chemokine receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003424943,0.0001138177,0.0003214092,0.0003209257,0.00001056562,0.00001068178,0.0001084957,0.00006146588,0.0004223677],"category_scores_gemma":[0.0000350676,0.0000854517,0.00006586156,0.0001167779,0.00009613981,0.0001112107,0.00002027155,0.0001614384,3.003405e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000225267,"about_ca_system_score_gemma":0.00021649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002164099,"about_ca_topic_score_gemma":0.0000203253,"domain_scores_codex":[0.9987288,0.00007806291,0.0004374364,0.0001289598,0.0005237152,0.0001031027],"domain_scores_gemma":[0.9990727,0.00007574537,0.0003186675,0.00007434265,0.0003869942,0.00007158235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009187596,0.0001930256,0.005471832,0.0001254735,0.00008098084,0.00004190168,0.0007992188,0.0009543871,0.9728802,0.000005775252,0.000009768293,0.01024983],"study_design_scores_gemma":[0.009222344,0.002027491,0.003237129,0.001352584,0.00002000403,0.00003176705,0.00008356027,0.0001409351,0.9835778,0.00007234298,0.0001718411,0.00006219798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950464,0.003267535,0.0008273905,0.0001496973,0.00009601666,0.0003071024,0.000006869922,0.000002246582,0.0002966822],"genre_scores_gemma":[0.9977171,0.001813728,0.0001227492,0.00002337526,0.00009617,0.00001154809,0.000002506302,0.00001698453,0.0001957922],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0106976,"threshold_uncertainty_score":0.462463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01537530646524145,"score_gpt":0.3273272014006939,"score_spread":0.3119518949354524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}